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首页> 外文期刊>Poultry Science >Enhancement of humoral immune responses to inactivated Newcastle disease and avian influenza vaccines by oral administration of ginseng stem-and-leaf saponins in chickens.
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Enhancement of humoral immune responses to inactivated Newcastle disease and avian influenza vaccines by oral administration of ginseng stem-and-leaf saponins in chickens.

机译：通过口服鸡中人参茎叶皂苷增强对灭活的新城疫和禽流感疫苗的体液免疫反应。

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摘要

Newcastle disease (ND) and avian influenza (AI) are common in the poultry industry. The objective of this study was to evaluate the effect of oral administration of ginseng stem-and-leaf saponins (GSLS) on the humoral immune responses of chickens to inactivated ND and AI vaccines. In experiment 1, oral administration of GSLS at a dose of 5 mg/kg of BW for 7 d on the immune response in chickens intramuscularly injected with inactivated ND vaccine was evaluated. Results showed that GSLS significantly increased the antibody level against ND in the serum of chickens. In experiment 2, the same regimen of GSLS was administered to chickens inoculated with inactivated AI vaccines, and an enhanced serum antibody response to AI vaccination was also observed. Considering the safety of GSLS, because no adverse effect was found throughout the experiments, GSLS may be a promising oral adjuvant to improve immunization in poultry.
机译：家禽业常见新城疫（ND）和禽流感（AI）。这项研究的目的是评估口服人参茎叶皂苷（GSLS）对鸡对灭活的ND和AI疫苗的体液免疫反应的影响。在实验1中，评估了肌肉注射ND灭活疫苗的鸡的口服GSLS剂量为5 mg / kg体重，持续7 d。结果表明，GSLS显着提高了鸡血清中抗ND的抗体水平。在实验2中，对接种灭活的AI疫苗的鸡施用了相同的GSLS方案，并且还观察到了对AI疫苗接种的增强的血清抗体反应。考虑到GSLS的安全性，因为在整个实验中均未发现不良反应，所以GSLS可能是提高家禽免疫性的有希望的口服佐剂。

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