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Radiographic and histologic evaluation of platelet-rich plasma and bovine-derived xenograft combination in bilateral sinus augmentation procedure

机译：富含血小板的血浆和牛源性异种移植物在双侧鼻窦增大手术中的放射学和组织学评价

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摘要

There is currently a great interest regarding the use of platelet-rich plasma (PRP) in combination with various bone graft materials in sinus lift procedures. The purpose of this study was to assess and compare the radiographic and histological results of sinus augmentation procedures following treatment with PRP/bovine-derived xenograft (BDX) vs. BDX/collagen membrane. Using a split mouth design, 10 patients, with ≤5 mm of residual alveolar bone in the vertical direction, were treated with PRP/BDX or BDX/collagen membrane. At 8 months after surgery, both graft materials led to a satisfactory increase in vertical dimensions of bone. Bone biopsies were taken from the augmented sites during the implant placement. Histological analysis demonstrated that majority of the trabecula contained orderly layered lamellar bone in the PRP/BDX group, whereas mainly woven bone with a haphazard arrangement of collagen fibers were noticed in the BDX /collagen membrane group. It can be concluded that both combinations resulted with a satisfactory bone height, but more prominent and mature bone formation was observed at sites treated with PRP/BDX.
机译：目前，对于在鼻窦提升手术中将富含血小板的血浆（PRP）与各种骨移植材料结合使用引起了极大的兴趣。这项研究的目的是评估和比较用PRP /牛源异种移植物（BDX）与BDX /胶原蛋白膜治疗后鼻窦增大手术的影像学和组织学结果。采用张口设计，对10例在垂直方向上残留牙槽骨≤5 mm的患者进行了PRP / BDX或BDX /胶原蛋白膜治疗。术后8个月，两种移植材料均导致骨骼垂直尺寸的令人满意的增加。在植入物放置期间，从扩大的部位取骨活检。组织学分析表明，在PRP / BDX组中，大多数小梁包含有序的层状层状骨，而在BDX /胶原膜组中，主要观察到胶原纤维随意排列的编织骨。可以得出结论，这两种组合均具有令人满意的骨高，但是在用PRP / BDX处理的部位观察到了更为突出和成熟的骨形成。

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