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Mean platelet volume in acute rheumatic fever

机译：急性风湿热的平均血小板量

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Acute rheumatic fever (ARF) is still an endemic disease, especially among school-aged children in developing countries. Mean platelet volume (MPV), which is commonly used as a measure of platelet size, indicates the rate of platelet production and platelet activation. We aimed to investigate MPV in children with ARF. The study population consisted of 40 children with ARF (32 patients with carditis and 8 patients without carditis) and 40 healthy control subjects. White blood cell (WBC) and platelet counts were significantly higher and MPV values were significantly lower in patients with ARF during the acute stage when compared to controls. Erythrocyte sedimentation rate (ESR) and C-reactive protein values significantly decreased in patients with ARF after the treatment when compared to baseline, whereas MPV values increased. MPV values were negatively correlated with ESR and WBC, and platelet counts. In conclusion, during the acute stage of ARF, MPV values were lower when compared to controls.
机译：急性风湿热（ARF）仍然是一种地方病，特别是在发展中国家的学龄儿童中。平均血小板体积（MPV）通常用于衡量血小板大小，它表示血小板生成和血小板活化的速率。我们旨在调查患有ARF的儿童的MPV。研究人群包括40名ARF儿童（32名心脏病患者和8名非心脏病患者）和40名健康对照组。与对照组相比，急性期ARF患者的白细胞（WBC）和血小板计数显着升高，MPV值显着降低。与基线相比，治疗后ARF患者的红细胞沉降率（ESR）和C反应蛋白值显着降低，而MPV值升高。 MPV值与ESR和WBC以及血小板计数呈负相关。总之，在ARF的急性期，MPV值低于对照组。

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