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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Questionnaire or Objective Assessment for Studying Exposure to Tobacco Smoke among Asthmatic and Healthy Children: The French VESTA Study.
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Questionnaire or Objective Assessment for Studying Exposure to Tobacco Smoke among Asthmatic and Healthy Children: The French VESTA Study.

机译:研究哮喘和健康儿童中烟尘暴露的问卷或客观评估:法国VESTA研究。

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摘要

Background. The underreporting of environmental tobacco smoke (ETS) exposure by parents of study children may depend on the instrument used and population studied, underlining the need for questionnaire validation in specific study settings. This study explores the validity of parent-reported ETS exposure in a French multicenter study on asthma.Methods. The study population was composed of 313 children ages 4 to 14 years. Exposure to ETS was evaluated both by questionnaires on recent ETS exposure and by assessment of urinary cotinine by an enzyme immunoassay.Results. According to parents' reports, about one-third of children were exposed to ETS within the past 2 days before cotinine measurement, and on average 14.9 +/- 15.4 cigarette-equivalent were smoked in their homes. The mean urinary cotinine was 435 +/- 530 nmol/mol creatinine and increased with the reported number of cigarette-equivalents smoked at home but it did not differ between children registered as being exposed to 1-10 cigarettes and children registered as unexposed. Agreement between questionnaire and urinary cotinine was moderate to poor according to our correlation coefficient (0.22) and kappa coefficient (0.09).Conclusion. These results show that our questionnaire is not discriminating enough to distinguish between nonexposure and mild exposure, but reveals gradients of higher exposure.
机译:背景。被研究儿童的父母对环境烟草烟雾(ETS)暴露的漏报可能取决于所使用的仪器和所研究的人群,这突显了在特定研究环境中需要进行问卷调查验证的必要性。这项研究探索了一项法国多中心哮喘研究中父母报告的ETS暴露的有效性。研究人群由313位4至14岁的儿童组成。通过最近的ETS暴露调查表以及通过酶免疫法评估尿可替宁来评估ETS暴露情况。根据父母的报告,在测量可替宁之前的两天内,约有三分之一的儿童接触了ETS,平均在家中吸烟的等效烟量为14.9 +/- 15.4。平均尿可替宁为435 +/- 530 nmol / mol肌酐,并随所报告的在家中吸烟的等效香烟数量而增加,但登记为接触1-10支香烟的儿童与未接触香烟的儿童之间无差异。根据我们的相关系数(0.22)和kappa系数(0.09),问卷与尿液可替宁之间的一致性为中度至较差。这些结果表明,我们的调查表不能充分区分非暴露和轻度暴露,但揭示了较高暴露的梯度。

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