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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Exercise protects against glucose intolerance in individuals with a small body size at birth.
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Exercise protects against glucose intolerance in individuals with a small body size at birth.

机译：运动可以防止出生时体型较小的人对葡萄糖的不耐受。

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Background. Small body size at birth is a risk factor for Type 2 diabetes. We investigated whether regular exercise is related to lower rates of glucose intolerance in individuals with a small body size at birth and whether birth size affects exercise habits in adulthood. Methods. Five hundred subjects aged 65-75 years with data on birth measurements underwent an oral glucose tolerance test. They reported their weekly exercise frequency and intensity and yearly physical leisure time activity. Results. Frequent (>/=3/week) or moderate weekly exercise and yearly physical activity were all related to lower rates of glucose intolerance. This effect was, however, dependent on birth size, being strongest among subjects with a small body size at birth (birth weight <==3000 g and/or ponderal index <==26 kg/m(3)). Among men, frequency (P = 0.033) and intensity (P = 0.030) of exercise as well as yearly physical activity (P = 0.005) correlated inversely with birth size. Conclusions. Subjects predisposed to Type 2diabetes due to a small birth size are strongly protected from glucose intolerance by regular exercise. Although a small body size at birth is related to a smaller muscle mass in adulthood, men born thin exercised more in adulthood than those not born thin. In these elderly subjects this might indicate the survival of the fittest.
机译：背景。出生时体型较小是2型糖尿病的危险因素。我们调查了定期运动是否与出生时体型较小的个体中较低的葡萄糖耐量发生率有关，以及出生年龄是否会影响成年后的运动习惯。方法。对500名年龄在65-75岁之间，具有出生测量数据的受试者进行了口服葡萄糖耐量测试。他们报告了他们每周的运动频率和强度以及每年的身体休闲时间活动。结果。频繁（> / = 3 /周）或适度的每周运动以及每年的体育锻炼都与较低的葡萄糖耐量率有关。然而，这种影响取决于出生的大小，在出生时体型较小的受试者中最强（出生体重<== 3000 g和/或子宫指数<== 26 kg / m（3））。在男性中，运动的频率（P = 0.033）和强度（P = 0.030）以及每年的体育锻炼（P = 0.005）与出生年龄成反比。结论。因小出生而易患2型糖尿病的受试者可通过定期锻炼来保护自己免受葡萄糖耐受不良的困扰。尽管出生时体型较小与成年后肌肉量较小有关，但瘦弱的人比不瘦弱的人运动更多。在这些老年受试者中，这可能表明适者生存。

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