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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Diet diversity and colorectal cancer.
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Diet diversity and colorectal cancer.

机译：饮食多样性和大肠癌。

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BACKGROUND: Food diversity has been recommended to achieve a healthy diet and prevent cancer. The relation between diet diversity and the risk of colorectal cancer was investigated using data from a multicenter case-control study carried out between 1992 and 1996 in Italy. METHODS: The study included 1225 subjects with cancer of the colon (688 men and 537 women), 728 with cancer of the rectum (437 men and 291 women), and 4154 controls (2073 men and 2081 women) residing in the same geographical areas. Odds ratios (ORs) of colon and rectal cancer and the corresponding 95% confidence intervals (CI) according to food diversity were derived from unconditional multiple logistic regression equations. RESULTS: For colon cancer, an inverse association for total diversity was found in males (adjusted OR of 0.65 for the highest vs the lowest quintile of total diversity; 95% CI: 0.46-0.93) and in females (OR = 0.85; 95% CI: 0.57-1.26). With respect to specific food groups, there was an inverse association only with diversity within vegetables (OR = 0.66; 95% CI: 0.54-0.81 in colon cancer and OR = 0.71; 95% CI: 0.55-0.91 in rectal cancer). CONCLUSIONS: This study suggests that total diversity is moderately related to a decreased risk of colorectal cancer risk. A better understanding of the potential influence of dietary patterns on colorectal cancer is needed. Copyright 2000 American Health Foundation and Academic Press.
机译：背景：已建议食物多样化以实现健康饮食并预防癌症。饮食多样性与大肠癌风险之间的关系，是根据1992年至1996年在意大利进行的一项多中心病例对照研究得出的数据进行调查的。方法：该研究纳入了1225名结肠癌患者（688名男性和537名女性），728名直肠癌患者（437名男性和291名女性）以及4154名对照患者（2073名男性和2081名女性） 。结肠癌和直肠癌的赔率（OR）和根据食物多样性的相应95％置信区间（CI）是从无条件多元logistic回归方程得出的。结果：对于结肠癌，男性的总多样性呈反相关关系（对于总多样性的最高五分位数与最低五分位数，校正后的OR为0.65; 95％CI：0.46-0.93）和女性（OR = 0.85; 95％ CI：0.57-1.26）。对于特定的食物类别，仅与蔬菜内的多样性呈负相关（结肠癌中OR = 0.66; 95％CI：0.54-0.81;直肠癌OR = 0.71; 95％CI：0.55-0.91）。结论：这项研究表明总多样性与降低结直肠癌风险的风险适度相关。需要更好地了解饮食方式对结直肠癌的潜在影响。版权所有2000美国健康基金会和学术出版社。

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