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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Associations of androgens with physical activity and fitness in young black and white men: the CARDIA Male Hormone Study.
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Associations of androgens with physical activity and fitness in young black and white men: the CARDIA Male Hormone Study.

机译：男性和年轻男性中雄激素与体育锻炼和健身的关系：CARDIA男性激素研究。

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OBJECTIVE: The association between physical activity or cardiovascular fitness and chronic disease risk in men might be mediated, in part, through androgens. Limited data exists on the potential associations of activity or fitness with serum hormones. We examined the associations of serum testosterone and sex hormone binding globulin (SHBG) concentrations with physical activity and cardiorespiratory fitness in black and white young men. METHOD: Data were collected from 391 black and 604 white male participants of the Coronary Artery Risk Development in (Young) Adults (CARDIA) Male Hormone Study aged 24-32 in 1992-1993. Cross-sectional associations of serum total testosterone (TT), bioavailable testosterone (BT) and SHBG levels with self-reported total physical activity score, and in a subset of men (n=617) with cardiorespiratory fitness measured via duration on a treadmill test were assessed. Five-year longitudinal associations of change in hormones with changes in physical activity also were examined.RESULTS: There were no cross-sectional or longitudinal associations of physical activity with SHBG, TT or BT in either black or white men. Fitness was positively associated with SHBG only in white men, but was not associated with TT or BT in either group. CONCLUSION: Overall the results do not support an association of self-reported physical activity with androgens, whereas they do suggest that fitness might be associated with SHBG in white men.
机译：目的：男性的体育锻炼或心血管健康状况与慢性病风险之间的关联可能部分是通过雄激素介导的。关于活动或健身与血清激素的潜在关联的有限数据。我们检查了黑人和白人年轻男性的血清睾丸激素和性激素结合球蛋白（SHBG）浓度与体育锻炼和心肺健康的关系。方法：从1992-1993年年龄在24-32岁之间的（年轻）成年人（CARDIA）男性激素研究的391位黑人和604位白人男性受试者中收集数据。血清总睾丸激素（TT），生物利用睾丸激素（BT）和SHBG水平与自我报告的总身体活动得分的横断面关系，以及在跑步机上通过持续时间测得的一部分心肺健康的男性（n = 617）被评估。结果还研究了激素变化与体力活动变化的五年纵向关联。结果：黑人或白人男性，体力活动与SHBG，TT或BT均无横断面或纵向关联。健身仅与白人男性中的SHBG呈正相关，但与两组中的TT或BT均不相关。结论：总的来说，该结果不支持自我报告的身体活动与雄激素的关联，而他们的确表明，健康可能与白人男性中的SHBG有关。

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