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Associations between regional socioeconomic deprivation and cancer risk: Analysis of population-based Cancer Registry data from Bavaria, Germany.

机译:区域社会经济剥夺与癌症风险之间的关联:来自德国巴伐利亚州的基于人群的癌症注册机构数据分析。

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OBJECTIVE: Previous research from other countries shows a positive association between cancer risk and regional deprivation. This study explores this association for lung and colorectal cancers in Germany. METHOD: Regional deprivation was assessed by the 'Bavarian Index of Multiple Deprivation'. Cancer data were provided by the Cancer Registry of Bavaria (2003-2006). The association between cancer risk and regional deprivation was evaluated by multilevel Poisson regression analysis. RESULTS: Crude incidence and mortality rates (per 1000 people) in the least deprived areas were 1.46 and 0.92 for lung cancer, 2.82 and 0.69 for colorectal cancer. For lung cancer, the age-adjusted relative risk (RR) for incidence in the most deprived districts (compared with the least deprived) in men was 1.41 (95% CI: 1.28-1.54), for mortality 1.59 (95% CI: 1.40-1.80); in women, an elevated RR was seen for mortality (1.24, 95% CI: 1.06-1.46). For colorectal cancer, the RR for incidence (men: 1.31, 95% CI: 1.17-1.46; women: 1.25, 95% CI: 1.12-1.40) and mortality (men: 1.51, 95% CI: 1.28-1.80; women: 1.49, 95% CI: 1.26-1.77) was always highest in the most deprived districts. CONCLUSION: At the district level in Bavaria, the risk for lung and colorectal cancers mostly increases with increasing regional deprivation.
机译:目的:其他国家的先前研究表明,癌症风险与区域贫困之间存在正相关关系。这项研究探索了德国肺癌和大肠癌的这种关联。方法:通过“巴伐利亚多重剥夺指数”评估区域剥夺。癌症数据由巴伐利亚州癌症登记处提供(2003-2006年)。通过多级泊松回归分析评估了癌症风险与区域剥夺之间的关联。结果:最贫困地区的粗发病率和死亡率(每千人)的肺癌分别为1.46和0.92,大肠癌为2.82和0.69。对于肺癌,男性中最贫穷的地区(与最贫穷的人群相比)的年龄校正相对风险(RR)为1.41(95%CI:1.28-1.54),死亡率为1.59(95%CI:1.40) -1.80);在女性中,死亡率的RR升高(1.24,95%CI:1.06-1.46)。对于结直肠癌,RR的发生率(男性:1.31,95%CI:1.17-1.46;女性:1.25,95%CI:1.12-1.40)和死亡率(男性:1.51,95%CI:1.28-1.80;女性: 1.49,95%CI:1.26-1.77)在最贫困的地区始终最高。结论:在巴伐利亚州的地区一级,随着区域贫困的增加,患肺癌和大肠癌的风险大多增加。

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