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Breast cancer screening: commentary and conclusions.

机译:乳腺癌筛查:评论和结论。

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摘要

None of the authors of this collection of invited papers on Breast Cancer Screening have seriously challenged the conclusion of the US Preventive Services Task Force (2009) that screening mammography should not be offered routinely to women age 40-49, and that it should be offered no more frequently than biennially to older women. However, several aspects of my questions (as listed in the Introduction) were not specifically addressed. Thus my question 1 ("Have all the concerns raised by some of the critics of the trials of breast cancer screening been adequately addressed by re-analyses that answer these concerns?") did not elicit any comment. I suspect this is because the response is largely in the negative. For example, in a recent update of the Swedish Two-County trial - where only three screens were used and then screening was offered to the controls - the authors simply ignored previous criticisms of their trial (Tabar et al., 2011). The report, published after any of the authors could have accessed it, shows a widening effect of mammography screening with time in this cluster-randomized trial and suggests that a basic imbalance between the groups was responsible for most if not all of the effect claimed for mammography screening.
机译:有关乳腺癌筛查的邀请论文集的作者中没有一个人对美国预防服务工作队(2009)的结论提出严峻的挑战,该结论是不应常规为40-49岁的女性提供乳房X线筛查,而应该提供对老年妇女而言,每两年一次的频率最高。但是,我的问题的几个方面(如引言中所列出的)并未具体解决。因此,我的问题1(“对乳腺癌筛查试验的一些批评者提出的所有关注是否已通过回答这些关注的重新分析得到了充分解决?”)没有引起任何评论。我怀疑这是因为回应很大程度上是负面的。例如,在瑞典两县试验的最新更新中-仅使用了三个屏幕,然后对对照进行了筛选-作者只是忽略了先前对其试验的批评(Tabar等,2011)。该报告在任何作者都可以使用后发表,显示了在这项整群随机试验中,随着时间的推移,乳腺X线摄影筛查的效果正在扩大,并且表明,各组之间的基本失衡是造成所声称的大部分(即使不是全部)影响的原因。乳腺X线摄影筛查。

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