• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Nonalcoholic fatty liver disease is associated with insulin resistance in a young Hispanic population.
【24h】

Nonalcoholic fatty liver disease is associated with insulin resistance in a young Hispanic population.

机译：非酒精性脂肪肝疾病与年轻的西班牙裔人群的胰岛素抵抗有关。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To investigate whether nonalcoholic fatty liver disease (NAFLD) is associated with insulin resistance (IR) in a young Hispanic population. METHODS: A cross-sectional study was performed in Bogota, Colombia, during 2006 in 263 males from the Colombian Air Force (age range 29-54 years). Anthropometric measurements and biochemical determinations (glycemia, lipid profile, insulin, and HOMA-IR) were obtained in order to determine the presence of metabolic syndrome (MS) criteria and insulin resistance in this population. In addition, ultrasound studies were performed to evaluate the presence of NAFLD. RESULTS: NAFLD was detected in 26.6% (n=70) of the subjects. Thirty four individuals had complete MS criteria (48.5%). The presence of NAFLD was associated with higher insulin levels (11.0+/-5.1 vs. 6.6+/-3.6, p=0.001), and its prevalence increased from 11% (n=8), to 24% (n=17) to 64% (n=45) from the lowest to the highest HOMA-IR tertile. Body mass index, triglycerides and subcutaneous and visceral fat were found to be independent predictors of NAFLD. CONCLUSIONS: These results suggest that NAFLD is associated with insulin resistance and extrahepatic adiposity in nondiabetic young Hispanic population.
机译：目的：探讨西班牙裔青年人群非酒精性脂肪肝（NAFLD）是否与胰岛素抵抗（IR）有关。方法：2006年在哥伦比亚波哥大进行了横断面研究，研究对象是来自哥伦比亚空军的263名男性（年龄在29-54岁之间）。获得人体测量学和生化测定值（血糖，脂质分布，胰岛素和HOMA-IR），以确定该人群中代谢综合征（MS）标准的存在和胰岛素抵抗。另外，进行了超声研究以评估NAFLD的存在。结果：在26.6％（n = 70）的受试者中检测到NAFLD。 34名患者具有完整的MS标准（48.5％）。 NAFLD的存在与较高的胰岛素水平相关（11.0 +/- 5.1与6.6 +/- 3.6，p = 0.001），其患病率从11％（n = 8）增加到24％（n = 17）从最低到最高HOMA-IR分位数增加到64％（n = 45）。体重指数，甘油三酸酯以及皮下和内脏脂肪是NAFLD的独立预测因子。结论：这些结果表明，NAFLD与非糖尿病性年轻西班牙裔人群的胰岛素抵抗和肝外肥胖有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号