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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >All-cause and cardiovascular mortality risk estimation using different definitions of metabolic syndrome in Lithuanian urban population
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All-cause and cardiovascular mortality risk estimation using different definitions of metabolic syndrome in Lithuanian urban population

机译：立陶宛城市人口使用代谢综合征的不同定义进行全因和心血管死亡风险评估

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Objective: The objective of the study was to assess mortality risk in the subjects with diagnosed metabolic syndrome (MS) using National Cholesterol Educational Program (NCEP-ATPIII), American Heart Association and National Heart Lung and Blood Institute (AHA/NHLBI) International Diabetes Federation (IDF) and Joint Interim Societies (JIS) definitions. Methods: Two random samples aged 35-64. years were examined in 1992-2002 in the framework within the Multinational Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA) study (N = 2455). The follow-up was carried out in terms of the end points reached from the baseline health examinations until December 31, 2009. Results: Cox regressions demonstrated that MS defined by IDF and JIS definitions remained the only significant determinants for all-cause mortality (RR = 1.48 and RR = 1.41; p < 0.05) and cardiovascular disease (CVD) mortality in men (RR = 1.81 and RR = 1.66; p < 0.05). In men (without previous CVD) the NCEP-ATPIII definition had increased mortality risk from CVD (RR = 1.98; p = 0.012), than in men with identified MS by the IDF and the new JIS definition. In women the MS was not associated with risk of mortality from CVD. Conclusion: The MS definitions according to the IDF and JIS criteria appear to be a slightly better predictor of all-cause mortality and mortality from CVD; MS according to the NCEP-ATPIII criteria appears to be a better predictor of mortality from CVD in men.
机译：目的：该研究的目的是使用美国国家胆固醇教育计划（NCEP-ATPIII），美国心脏协会和美国国家心肺与血液研究所（AHA / NHLBI）国际糖尿病评估诊断为代谢综合征（MS）的受试者的死亡风险联邦（IDF）和联合临时协会（JIS）的定义。方法：两个年龄在35-64岁之间的随机样本。在1992-2002年间，在“心血管疾病趋势和决定因素跨国监测”研究（N = 2455）的框架下对这些基因进行了研究。根据从基线健康检查到2009年12月31日达到的终点进行了随访。结果：Cox回归表明IDF和JIS定义的MS仍然是全因死亡率（RR）的唯一重要决定因素= 1.48，RR = 1.41; p <0.05）和男性心血管疾病（CVD）死亡率（RR = 1.81和RR = 1.66; p <0.05）。与IDF和新JIS定义确定MS的男性相比，NCEP-ATPIII定义的男性（无先前的CVD）患心血管疾病的死亡风险增加（RR = 1.98; p = 0.012）。在女性中，MS与CVD的死亡风险无关。结论：根据IDF和JIS标准的MS定义似乎可以更好地预测全因死亡率和CVD的死亡率。根据NCEP-ATPIII标准的MS似乎是男性CVD死亡率更好的预测指标。

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