• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Preventive Veterinary Medicine >Seroprevalence and sero-conversion after vaccination against Peste des Petits Ruminants in sheep and goats from Awash Fentale District, Afar, Ethiopia.
【24h】

Seroprevalence and sero-conversion after vaccination against Peste des Petits Ruminants in sheep and goats from Awash Fentale District, Afar, Ethiopia.

机译：埃塞俄比亚阿法尔Awash Fentale区对绵羊和山羊的小反刍兽疫疫苗接种后的血清阳性率和血清转化。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A cross-sectional epidemiological study followed by vaccination and postvaccinal serum antibody assessment against Peste des Petits Ruminants (PPR) in small ruminant population of Awash Fentale District, Afar, Ethiopia, was conducted from September 2006 to June 2007 with the aim of investigating seroprevalence and post-vaccination sero-conversion rate. A total of 1239 sera collected from sheep and goats which were not vaccinated, were screened by using nucleoprotein-based competitive enzyme-linked immunosorbent assay (c-ELISA). Only 21 (1.70%) animals were found to be positive. Following the base-line seroprevalence study, small ruminants in the area were vaccinated using the attenuated homologous PPR virus (Nigeria 75/1) strain vaccine, produced at National Veterinary Institute (NVI) in Debre-Zeit, Ethiopia. A total of 1096 small ruminants were resampled from the vaccinated population fourteen days after vaccination. The postvaccination sero-conversion rate in the population was found to be 61.13%, indicating a relatively weak herd immunity. The main reason for the low sero-conversion could be the thermolabile nature of the vaccine, since no statistically significant difference was observed between small ruminants vaccinated by Veterinary Professionals and Community Animal Health Workers (CAHWs), using Chi-squared test at 95% CI (P
机译：于2006年9月至2007年6月进行了横断面流行病学研究，随后进行了疫苗接种和疫苗接种后针对埃塞俄比亚阿法尔Awash Fentale区小反刍动物小反刍兽疫（PPR）的血清抗体评估，旨在调查血清阳性率和疫苗接种后的血清转化率。使用基于核蛋白的竞争性酶联免疫吸附测定法（c-ELISA）筛选了未接种羊和山羊的1239份血清。仅发现21只（1.70％）动物呈阳性。在进行基线血清阳性率研究之后，使用由埃塞俄比亚德布勒-泽特的国家兽医研究所（NVI）生产的减毒同源PPR病毒（Nigeria 75/1）株疫苗对该地区的小反刍动物进行了疫苗接种。接种后十四天，从接种人群中重新取样了总共1096只小反刍动物。人群中接种疫苗后的血清转化率为61.13％，表明畜群免疫力相对较弱。血清转化率低的主要原因可能是疫苗的耐热性，因为在95％CI的卡方检验下，兽医专业人员和社区动物卫生工作者（CAHW）接种的小反刍动物之间没有观察到统计学上的显着差异。 （ P

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号