首页> 外文期刊>Proceedings of the Nutrition Society >Obesity, sarcopenia and their functional consequences in old age.
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Obesity, sarcopenia and their functional consequences in old age.

机译:肥胖,肌肉减少症及其在老年人中的功能后果。

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摘要

The prevalence of obesity is high in older persons and recent trends show a rapid increase in this prevalence. Results from observational and intervention studies (i.e. weight loss studies) show the strong negative impact of obesity on functional status in old age. There are different potential pathways through which obesity may lead to functional decline in older persons. Furthermore, the presence of overweight and obesity during the life course and trends in medical care are likely to influence the impact of obesity on disability. The concepts sarcopenia (age-related loss of muscle mass) and dynapenia (age-related loss of muscle strength) receive a lot of research attention as potential determinants of functional decline in old age. There is no consensus on the definitions of these concepts. Recent studies conducted in large cohort studies of mainly community-dwelling older persons show that poor muscle strength is strongly associated with functional decline compared to low muscle mass. In several studies, no association between muscle mass and functional status was observed. Current research on the combination of obesity with poor muscle strength (dynapenic-obesity) suggests a potential additive effect of both components on poor functional status in old age which seems independent of the level of physical activity.
机译:肥胖症的患病率在老年人中很高,最近的趋势表明,这种患病率迅速增加。观察和干预研究(即体重减轻研究)的结果表明,肥胖对老年人的功能状态具有强烈的负面影响。肥胖可能导致老年人功能下降的途径不同。此外,一生中超重和肥胖的存在以及医疗护理的趋势可能会影响肥胖对残疾的影响。肌肉减少症(与年龄相关的肌肉质量丧失)和运动障碍(与年龄相关的肌肉力量丧失)的概念作为老年功能下降的潜在决定因素而受到了很多研究的关注。这些概念的定义尚无共识。在主要针对居住社区的老年人的大型队列研究中,最近进行的研究表明,与低肌肉质量相比,不良的肌肉强度与功能下降密切相关。在一些研究中,没有观察到肌肉质量与功能状态之间的关联。肥胖与肌肉强度差(运动障碍性肥胖症)结合的最新研究表明,这两种成分对老年人机能状况差的潜在加性作用,似乎与体育锻炼的水平无关。

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