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首页> 外文期刊>Progress in Cardiovascular Diseases >The uncertain significance of low vitamin D levels in African descent populations: A review of the bone and cardiometabolic literature
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The uncertain significance of low vitamin D levels in African descent populations: A review of the bone and cardiometabolic literature

机译:低维生素D水平在非洲人后裔中的不确定意义:骨骼和心脏代谢文献综述

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摘要

Vitamin D levels in people of African descent are often described as inadequate or deficient. Whether low vitamin D levels in people of African descent lead to compromised bone or cardiometabolic health is unknown. Clarity on this issue is essential because if clinically significant vitamin D deficiency is present, vitamin D supplementation is necessary. However, if vitamin D is metabolically sufficient, vitamin D supplementation could be wasteful of scarce resources and even harmful. In this review vitamin D physiology is described with a focus on issues specific to populations of African descent such as the influence of melanin on endogenous vitamin D production and lactose intolerance on the willingness of people to ingest vitamin D fortified foods. Then data on the relationship of vitamin D to bone and cardiometabolic health in people of African descent are evaluated.
机译:非洲人后裔的维生素D水平通常被描述为不足或不足。在非洲人后裔中低维生素D是否会导致骨骼或心脏代谢健康受损,这一点尚不清楚。在这个问题上的明确性至关重要,因为如果存在临床上明显的维生素D缺乏症,则必须补充维生素D。但是,如果维生素D在代谢上足够,那么补充维生素D可能会浪费稀缺的资源,甚至有害。在这篇综述中,维生素D的生理学着重于非洲人后裔的特定问题,例如黑色素对内源性维生素D产生的影响以及乳糖不耐症对人们摄入维生素D强化食品的意愿。然后评估非洲人后裔维生素D与骨骼和心脏代谢健康之间关系的数据。

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