New disc-based technologies for diagnostic and research applications.

Barathur R; Bookout J; Sreevatsan S; Gordon J; Werner M; Thor G; Worthington M

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New disc-based technologies for diagnostic and research applications.

机译：用于诊断和研究应用程序的基于光盘的新技术。

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The role of genotypic analysis in disease diagnostics and drug response assessment is continually expanding. New genomic discoveries combined with new, novel technologies may provide a greater range of testing capabilities in the near future. We describe the application of nanotechnology, in which DNA microarrays have been placed in a microchannel environment that can be read and analyzed in an optical (CD/DVD) disc drive system. The potential exists to combine molecular and immunological applications together into a rapid, low-cost, high-capacity screening platform. The relevance of this technology is discussed in respect to infectious agent detection, pharmacogenomics, neurogenomics and genetic variations associated with neurologic diseases.

机译：基因型分析在疾病诊断和药物反应评估中的作用正在不断扩大。新的基因组发现与新的，新颖的技术相结合，可能会在不久的将来提供更大范围的测试功能。我们描述了纳米技术的应用，其中将DNA微阵列置于微通道环境中，该环境可以在光学（CD / DVD）光盘驱动器系统中读取和分析。将分子和免疫学应用结合在一起成为快速，低成本，高容量的筛选平台的潜力。讨论了该技术在传染原检测，药物基因组学，神经基因组学以及与神经系统疾病相关的遗传变异方面的相关性。

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《Psychiatric genetics》 |2002年第4期|共14页
作者
Barathur R; Bookout J; Sreevatsan S; Gordon J; Werner M; Thor G; Worthington M;
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正文语种 eng
中图分类医学遗传学;
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New; Research; nanotechnology; drug response; novel; 研究;

机译：新;研究;纳米技术;药物反应;新颖;研究;

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New disc-based technologies for diagnostic and research applications.

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