...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Progress in brain research >Pregnancy and post partum: changes in cognition and mood.
【24h】

Pregnancy and post partum: changes in cognition and mood.

机译：怀孕和产后：认知和情绪的变化。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Steroidal hormones are increasingly recognized as highly relevant in multiple aspects of brain functioning. While basic science has actively worked to advance understanding of fundamental steroid mechanisms within the brain, investigation of the neurobehavioral outcomes of reproductive hormone actions on the human brain has received less attention. We argue that the dramatic steroidal hormone changes seen in human reproduction must be systematically studied and may provide novel explanations of cognitive and mood disorders associated with reproductive events. This chapter provides a review of current literature establishing a role for a variety of steroids on neuroactivity, and evidence from a variety of observational and experimental paradigms linking hormones and clinical aspects of cognition and mood in humans. The specific hormonal changes of pregnancy are described and discussed in relation to concomitant alterations in cognition and mood across the peri-natal period. A review of studies that have systematically observed cognitive and affective changes both during pregnancy and the post-partum period is presented, as well as new data that follow a small cohort of women for an extended period of time after delivery. We conclude that women may show specific areas of cognitive changes during and after pregnancy, notably deficits in verbal learning and memory. Mood appears to be impacted as well. While steroidal hormones show a pattern of associations with mood during and after pregnancy, no such pattern is evident for cognition. The embryonic state of our knowledge regarding reproductive hormones and neurobehavioral functioning is evident, as are the scientific and public health reasons to redress this lacuna.
机译：甾体激素在脑功能的多个方面越来越被认为是高度相关的。虽然基础科学积极地致力于增进对大脑内基本类固醇机制的了解，但对生殖激素作用在人脑上的神经行为结果的研究却很少受到关注。我们认为，必须对人类生殖系统中甾体激素的戏剧性变化进行系统研究，并可能为与生殖事件有关的认知和情绪障碍提供新颖的解释。本章回顾了建立各种类固醇在神经活动中作用的现有文献，并提供了各种将激素与人类认知和情绪的临床方面联系起来的观察和实验范式的证据。关于围产期期间认知和情绪的伴随变化，对妊娠的特定激素变化进行了描述和讨论。介绍了一项研究的综述，这些研究系统地观察了妊娠和产后期间的认知和情感变化，以及一些新的数据，这些数据追踪了一小群妇女在分娩后很长一段时间。我们得出的结论是，妇女可能在怀孕期间和之后表现出特定的认知变化区域，尤其是言语学习和记忆能力下降。心情似乎也受到影响。虽然类固醇激素在怀孕期间和之后显示出与情绪相关的模式，但没有这种模式可用于认知。我们对生殖激素和神经行为功能的了解处于萌芽状态，科学和公共卫生理由也可以弥补这一缺陷。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号