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首页> 外文期刊>Progress in brain research >Plasticity in brain processing and modulation of pain.
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Plasticity in brain processing and modulation of pain.

机译：大脑加工和疼痛调节中的可塑性。

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Brain processing of pain in humans is based on multiple ascending pathways and brain regions that are involved in several pain components, such as sensory, immediate affective, and secondary affective dimensions. These dimensions are processed both serially and in parallel. They include spinal ascending pathways that directly target limbic and brainstem structures involved in pain-related emotions as well as a pathway proceeding from the somatosensory cortices to limbic cortical areas. Superimposed on this neural organization is the capacity to process the dimensions of pain in multiple ways, as in patients who lack one cerebral hemisphere but can nevertheless locate and rate pain intensity and pain unpleasantness on both sides of the body. The dimensions of pain also can be psychologically modulated in multiple ways and these changes are accompanied by corresponding changes in relevant brain structures. Finally, understanding psychological modulation of pain and pain-related brain activity is optimized by a scientific framework that integrates principles of contemporary physics, neuroscience, and human experiential science.
机译：人类对疼痛的大脑处理基于多个上升途径和大脑区域，这些途径和区域涉及多个疼痛成分，例如感觉，即时情感和继发情感维度。这些尺寸可以串行和并行处理。它们包括直接针对涉及疼痛相关情绪的边缘和脑干结构的脊柱上升途径，以及从体感皮质到边缘皮质区域的途径。在这种神经组织上叠加着以多种方式处理疼痛的能力，例如在缺乏一个大脑半球但仍然可以定位并评估身体两侧疼痛强度和疼痛不适的患者中。疼痛的程度也可以通过多种方式在心理上进行调节，这些变化伴随着相关脑结构的相应变化。最后，通过整合了当代物理学，神经科学和人类体验科学原理的科学框架，优化了对疼痛和与疼痛相关的大脑活动的心理调节。

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