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Anaemia, iron deficiency and vitamin A status among school-aged children in rural Kazakhstan

机译:哈萨克斯坦农村学龄儿童的贫血,铁缺乏和维生素A状况

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摘要

Objectives: To investigate the prevalence of anaemia and iron deficiency and vitamin A status among school-aged children in rural Kazakhstan and identify factors associated with anaemia in this population.Design: A cross-sectional design.Setting: School-aged children in rural Kazakhstan.Subjects: Socio-economic and anthropometric information was collected from 159 school-aged children living in the Kzyl-Orda region of Kazakhstan. Blood samples were collected and the concentrations of haemoglobin (Hb), serum iron, serum ferritin (SF), erythrocyte protoporphyrin (EP), serum retinol and beta-carotene, total iron binding capacity (TIBC), transferrin saturation (TS) and other haematological indices were measured.Results: Among the 159 children, the prevalence of anaemia and iron deficiency defined by the multiple criteria model (SF, TS and EP) was 27% and 13%, respectively. Nine per cent had iron-deficiency anaemia and 21% had serum retinol value <1.05 mumol l(-1). Mean SF and serum iron concentrations and TS were significantly lower in anaemic children than in their non-anaemic peers, while TIBC and EP were significantly higher in children with anaemia. Hb was significantly correlated with serum iron and retinol concentrations. Serum retinol and SF concentrations and mean corpuscular volume were significantly correlated with Hb by multiple regression analysis.Conclusions: Anaemia among school-aged children in rural Kazakhstan appears to be related to iron indices and vitamin A status.
机译:目的:调查哈萨克斯坦农村学龄儿童的贫血,铁缺乏和维生素A的患病率,并确定该人群中与贫血相关的因素设计:横断面设计背景:哈萨克斯坦农村学龄儿童受试者:从生活在哈萨克斯坦Kzyl-Orda地区的159名学龄儿童收集了社会经济和人体测量学信息。收集血液样本,并测定血红蛋白(Hb),血清铁,血清铁蛋白(SF),红细胞原卟啉(EP),血清视黄醇和β-胡萝卜素的浓度,总铁结合能力(TIBC),转铁蛋白饱和度(TS)等结果:在159名儿童中,多标准模型(SF,TS和EP)定义的贫血和铁缺乏症患病率分别为27%和13%。 9%的人患有缺铁性贫血,而21%的人的血清视黄醇值<1.05 mumol l(-1)。贫血儿童的平均SF,血清铁浓度和TS明显低于非贫血的儿童,而TIBC和EP则明显高于贫血儿童。血红蛋白与血清铁和视黄醇浓度显着相关。多元回归分析表明,血清视黄醇和SF的浓度以及平均红细胞体积与血红蛋白显着相关。结论:哈萨克斯坦农村学龄儿童贫血似乎与铁指数和维生素A水平有关。

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