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首页> 外文期刊>Public Health Nutrition >Overall glycaemic index and glycaemic load of habitual diet and risk of heart disease.
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Overall glycaemic index and glycaemic load of habitual diet and risk of heart disease.

机译：习惯饮食的总体血糖指数和血糖负荷以及患心脏病的风险。

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Objective. To test the hypothesis that diets with high glycaemic index (GI) and glycaemic load (GL) increase the risk of heart disease. Design. Overall GI and GL were assessed from 7 d diet records or diet history interviews. Setting. Information on hospitalization and death due to CVD and CHD was obtained from the National Register of Cause of Death and the National Register of Patients. Subjects. In total 3959 adult Danes were - depending on time of entry - followed for 6-25 years until 31 December 1999. Results. Overall GI was inversely associated with heart disease in men. The hazard ratios (95% CI) for the 10th and 90th GI percentiles compared with the median were 1.38 (1.13, 1.68) and 0.90 (0.76, 1.07) for CVD morbidity, 1.45 (1.05, 1.99) and 0.81 (0.62, 1.06) for CVD mortality, and 1.31 (0.97, 1.76) and 0.65 (0.51, 0.84) for CHD morbidity. In male subjects GL was not associated with either outcome. In women no clear association between overall GI and heart disease was found, whereas positive non-linear associations were found for GL: at very high levels of GL, increase in GL was associated with increasing CVD and CHD morbidity. Conclusions. In men low-GI diets were associated increased risk of heart disease and GL was not associated with heart disease. In women there was no clear association between GI and heart disease, but to some extent a positive association between GL and heart disease was observed as hypothesized.
机译：目的。为了检验以下假设：高血糖指数（GI）和高血糖负荷（GL）的饮食会增加患心脏病的风险。设计。从7 d饮食记录或饮食史访谈中评估总体GI和GL。设置。有关由CVD和CHD引起的住院和死亡的信息可从国家死亡原因登记簿和国家患者登记簿中获得。主题。根据入境时间，总共3959名成年丹麦人接受了6到25年的跟踪检查，直到1999年12月31日为止。结果。总体胃肠道与男性心脏病呈负相关。第十和第90 GI百分位数与中位数的危险比（95％CI）为1.38（1.13，1.68）和0.90（0.76，1.07），CVD发病率为1.45（1.05，1.99）和0.81（0.62，1.06） CVD死亡率分别为1.31（0.97，1.76）和0.65（0.51，0.84）。在男性受试者中，GL与任一结局均无关。在女性中，没有发现总的GI与心脏病之间有明确的关联，而在GL中发现了正的非线性关联：在非常高的GL水平下，GL的增加与CVD和CHD发病率的增加有关。结论。在男性中，低GI饮食与心脏病风险增加有关，而GL与心脏病无关。在女性中，胃肠道与心脏病之间没有明确的关联，但是在一定程度上可以推测，GL与心脏病之间呈正相关。

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