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Perceptions of sexual risk compensation following posttrial HIV vaccine uptake among young South Africans

机译：南非青年人服用艾滋病毒疫苗后对性风险补偿的看法

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Concerns about the impact of risk compensation on advances in biomedical human immunodeficiency virus (HIV) prevention technologies have been documented. We conducted an exploratory qualitative study using focus group discussions with young South African men and women (aged 18 to 24 years) to explore perceptions of risk compensation with regard to a hypothetical posttrial HIV vaccine. During the discussions, participants expressed their disquiet about the potential for risk compensation and the manner in which this might manifest among young people. Discussions specifically focused on reductions in condom use, an increase in multiple partners, and increased frequency of sex. The discussions also revealed contradictory feelings about HIV vaccines: appreciation for their development tempered by concerns about loss of control and undermining morality. Women were particularly concerned with the possibility of increased partner concurrency and infidelity. We suggest that concerns in HIV vaccine target populations about the impact of possible risk compensation be incorporated into strategies for vaccine introduction once vaccines move from the hypothetical to reality.
机译：关于风险补偿对生物医学人类免疫缺陷病毒（HIV）预防技术进步的影响的担忧已得到记录。我们进行了探索性定性研究，使用了与年轻的南非男性和女性（年龄在18至24岁之间）进行的焦点小组讨论，以探讨假想的HIV疫苗对风险补偿的看法。在讨论中，与会人员对风险补偿的潜力及其在年轻人中表现出来的方式表示了不安。讨论特别集中在减少使用安全套，增加多个伴侣以及增加性行为频率上。讨论还揭示了人们对HIV疫苗的矛盾看法：由于担心失去控制和破坏道德，对疫苗的发展表示赞赏。妇女尤其担心伴侣并发和不忠的可能性增加。我们建议，一旦疫苗从假设变为现实，就将可能的风险补偿的影响纳入对HIV疫苗目标人群的关注之中。

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