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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Hypocapnia associated with cardiac stress scintigraphy in chest pain patients with panic disorder.
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Hypocapnia associated with cardiac stress scintigraphy in chest pain patients with panic disorder.

机译：惊恐症胸痛患者的低碳酸血症与心脏压力闪烁显像有关。

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摘要

OBJECTIVE: Patients with recurrent chest pain but no evidence of coronary artery disease often meet diagnostic criteria for panic disorder (PD). However, it can be argued that the phenomenological diagnosis of PD may not be valid in these normal coronary chest pain (NCCP) patients. The purpose of this study is to additionally validate the diagnosis of PD in chest pain patients by comparing PCO2 levels before and during myocardial stress scintigraphy in those with and without PD. METHOD: End-tidal PCO2 was measured before and during myocardial stress scintigraphy in 22 patients being evaluated for chest pain. Psychiatric diagnoses were assessed by structured interview. RESULTS: Eleven of the 19 patients (58%) with negative scintigrams met DSM-III-R diagnostic criteria for current panic disorder. Prestress PCO2 levels were significantly lower in these patients. Eight of the nine NCCP patients with prestress PCO2 < 34 mm Hg had PD. CONCLUSIONS: The finding of stress-related hypocapnia associated with PD in NCCP patients provides additional support for the validity of the diagnosis of PD in this population. The potential value of PCO2 measurements in screening for PD in patients with chest pain merits additional study.
机译：目的：患有反复发作性胸痛但无冠心病证据的患者通常符合恐慌症（PD）的诊断标准。但是，可以争论的是，PD的现象学诊断可能对这些正常的冠心病（NCCP）患者无效。这项研究的目的是通过比较患有和不患有PD的患者在进行心肌压力闪烁显像之前和期间的PCO2水平，从而进一步验证胸痛患者中PD的诊断。方法：在22例评估胸痛的患者中，在进行心肌压力闪烁显像之前和期间测量了潮气末PCO2。通过结构化面谈评估精神病诊断。结果：19例闪烁闪烁图阴性的患者中有11例（58％）符合当前恐慌症的DSM-III-R诊断标准。这些患者的预应力PCO2水平显着降低。 9名预应力PCO2 <34 mm Hg的NCCP患者中有8名患有PD。结论：在NCCP患者中发现与PD相关的压力相关性低碳酸血症为该人群PD诊断的有效性提供了额外的支持。 PCO2测量值在筛查胸痛患者的PD中的潜在价值值得进一步研究。

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