首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Depressive symptoms and metabolic risk in adult male twins enrolled in the National Heart, Lung, and Blood Institute twin study.
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Depressive symptoms and metabolic risk in adult male twins enrolled in the National Heart, Lung, and Blood Institute twin study.

机译:美国国家心脏,肺和血液研究所双胞胎研究的成年男性双胞胎有抑郁症状和代谢风险。

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OBJECTIVE: To determine the extent to which depressive symptoms are associated with metabolic risk factors and whether genetic or environmental factors account for this association. METHOD: Twin structural equation modeling was employed to estimate genetic and environmental contributions to the covariation of depressive symptoms, as indexed by the Centers for Epidemiological Studies-Depression Scale, and common variance among blood pressure, body mass index, waist-to-hip ratio, and serum triglycerides and glucose among 87 monozygotic and 86 dizygotic male twin pairs who participated in the NHLBI twin study. RESULTS: Depressive symptoms were associated with individual components of the metabolic syndrome and common variance among the risk factors. Twin structural equation modeling indicated that the associations were attributable to environmental (nongenetic) factors. CONCLUSIONS: These results support the hypothesis that depressive symptoms may increase risk for a pattern of physiological risk consistent with the metabolic syndrome.
机译:目的:确定抑郁症状与代谢危险因素相关的程度,以及遗传因素或环境因素是否引起这种关联。方法:根据流行病学研究中心-抑郁量表以及血压,体重指数,腰臀比之间的常见差异,采用双结构方程模型来估算遗传和环境因素对抑郁症状的协变的影响。 ,以及参加NHLBI双胞胎研究的87对单卵双生和86对双卵双生男性双胞胎中的血清甘油三酸酯和葡萄糖。结果:抑郁症状与代谢综合征的各个组成部分和危险因素之间的共同差异有关。孪生结构方程建模表明,该关联可归因于环境(非遗传)因素。结论:这些结果支持以下假设,即抑郁症状可能增加与代谢综合征相符的生理风险模式的风险。

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