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Does writing affect asthma? A randomized trial.

机译:写作会影响哮喘吗?一项随机试验。

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OBJECTIVE: Nonpharmacologic treatments for asthma may act as useful adjuncts to pharmacotherapy but should be recommended to patients only after several well-controlled studies provide evidence of efficacy. Research demonstrating that written emotional expression can improve pulmonary function in patients with asthma consists of one impressive yet unreplicated study. Our main objective was to test and extend previous research finding that written emotional expression improves pulmonary function in patients with asthma compared with writing on neutral topics. METHODS: We conducted a randomized, controlled trial of outpatient asthmatics recruited from hospitals and the community. Of the 137 adult patients with asthma who were randomized, 117 began and 114 completed the study. Patients were randomly assigned to write for 20 minutes, once per week, for 3 weeks about stressful experiences (n = 41), positive experiences (n = 37), or neutral experiences (n = 36; control group). At baseline, postintervention, and 2-month follow up, patients were assessed by spirometry. RESULTS: The mean change from baseline to 2-month follow up in percentage of predicted forced expiratory volume in 1 second (FEV1) was 4.2% in the stress-writing group, 1.3% in the positive-writing group, and 3.0% in the control group. In forced vital capacity (FVC), there was 3.1% improvement in the stress-writing group, 3.6% in the positive-writing group, and 2.4% in the control group. These changes were not statistically or clinically significant. CONCLUSIONS: The present study reduces confidence in the ability of written emotional expression to benefit the disease status of asthma patients.
机译:目的:哮喘的非药物治疗可能是药物治疗的有用辅助手段,但只有在进行了数个对照良好的研究后,才应向患者推荐。研究表明书面情绪表达可以改善哮喘患者的肺功能,这项研究涉及一项令人印象深刻但没有重复的研究。我们的主要目标是测试和扩展先前的研究发现,与在中性话题上写作相比,书面情感表达可以改善哮喘患者的肺功能。方法:我们对医院和社区招募的门诊哮喘患者进行了一项随机对照试验。在137名随机分组的成年哮喘患者中,有117名开始并114名完成了研究。随机分配患者20分钟,每周一次,共3周,涉及压力经历(n = 41),积极经历(n = 37)或中立经历(n = 36;对照组)。在基线,干预后和2个月的随访中,通过肺活量测定法评估患者。结果:应激写作组从基线到2个月随访的平均强迫呼气量百分比(FEV1)的平均变化为4.2%,积极写作组为1.3%,积极写作组为1.3%。控制组。在强迫肺活量(FVC)中,压力写作组提高了3.1%,积极写作组提高了3.6%,对照组提高了2.4%。这些变化在统计学或临床上均无统计学意义。结论:本研究降低了书面情绪表达有益于哮喘患者疾病状态的能力的信心。

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