• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Salivary cortisol as a predictor of postoperative fatigue.
【24h】

Salivary cortisol as a predictor of postoperative fatigue.

机译：唾液皮质醇可预测术后疲劳。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: Some patients with chronic fatigue syndrome (CFS) exhibit low basal cortisol levels, but it is not known whether low cortisol is a cause of CFS, predates the onset of CFS symptoms, or is an epiphenomenon caused by the behavioral changes typical of CFS. Because elective surgery is one of the few predictable risk factors for chronic fatigue, in this study, we followed a cohort of surgery patients from before to 6 months after their operation to test these theories. METHOD: One hundred sixty-one patients completed fatigue questionnaires and provided salivary cortisol samples before undergoing an elective inpatient surgical procedure, and then 2 days, 3 weeks, and 6 months afterward. RESULTS: Controlling for relevant demographic and surgical variables and for preoperative fatigue, low preoperative cortisol did not predict postoperative fatigue severity on any occasion (p > .05). Similarly, there was no correlation between low postoperative cortisol and postoperative fatigue severity at 3 weeks or 6 months (p > .05). Although 16 patients met our case definition for "chronic fatigue" at the 6-month follow up, low preoperative and low postoperative cortisol did not significantly predict fatigue caseness (p > .05). CONCLUSIONS: Any association between chronic fatigue and low cortisol would seem to develop after the onset of fatigue symptoms. Low cortisol is therefore unlikely to be the primary cause of chronic fatigue states.
机译：目的：一些患有慢性疲劳综合征（CFS）的患者表现出低的基础皮质醇水平，但尚不清楚低皮质醇是否是CFS的病因，早于CFS症状发作，还是由CFS典型行为改变引起的表象现象。由于择期手术是少数几个可预测的慢性疲劳风险因素之一，因此在本研究中，我们对一组手术患者从手术前到手术后6个月进行了随访，以检验这些理论。方法：161名患者在进行选择性住院手术之前，之后的2天，3周和6个月内，完成了疲劳问卷并提供了唾液皮质醇样品。结果：控制相关的人口统计学和手术变量以及术前疲劳，术前低皮质醇水平不能在任何情况下预测术后疲劳的严重程度（p> .05）。同样，术后3周或6个月时低皮质醇水平与术后疲劳严重程度之间也没有相关性（p> .05）。尽管在6个月的随访中有16例患者符合我们对“慢性疲劳”的病例定义，但术前和术后低皮质醇水平均不能显着预测疲劳病例（p> .05）。结论：疲劳症状发作后，似乎会出现慢性疲劳和低皮质醇之间的任何联系。因此，低皮质醇可能不会成为慢性疲劳状态的主要原因。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号