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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease.
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Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease.

机译：冠心病患者的恐惧性焦虑，抑郁和室性心律失常的风险。

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OBJECTIVE: Findings of an association between phobic anxiety and elevated risks of sudden cardiac death suggest that phobic anxiety may be related to increased risk of ventricular arrhythmias. The purpose of this study was to examine whether phobic anxiety is associated with ventricular arrhythmias in patients with documented coronary artery disease (CAD). METHODS: Phobic anxiety level was measured using the Crown-Crisp phobic anxiety scale in 940 patients (660 men, 280 women) hospitalized for diagnostic cardiac catheterization between April 1999 and June 2002. Depressive symptomatology was assessed using the Beck Depression Inventory. Patients were followed for a median follow-up period of 3 years, and the occurrence of ventricular arrhythmias was determined through review of medical records. RESULTS: Ventricular arrhythmias occurred in 97 patients and were significantly related to higher phobic anxiety after statistical adjustment for established medical and demographic determinants of arrhythmias (odds ratio = 1.40; p = .012). Depressive symptomatology was significantly correlated with phobic anxiety (r = 0.44, p < .001) and was also related to ventricular arrhythmias (odds ratio = 1.40; p = .006). The composite of depression and phobic anxiety predicted ventricular arrhythmias with a larger effect size than either depression or phobic anxiety score alone (odds ratio = 1.6, 95% confidence interval, 1.2-2.1, p = .002). CONCLUSIONS: Both phobic anxiety and depressive symptomatology predict ventricular arrhythmias in patients with CAD and may share a common factor predictive of ventricular arrhythmias.
机译：目的：恐惧症与心脏猝死风险升高之间的关联性研究表明，恐惧症可能与室性心律不齐的风险增加有关。这项研究的目的是检查患有冠心病（CAD）的患者的恐惧性焦虑是否与室性心律失常有关。方法：使用Crown-Crisp恐惧焦虑量表对1999年4月至2002年6月住院的诊断性导管置入术的940例患者（660例男性，280例女性）的恐惧焦虑水平进行了测量。使用贝克抑郁量表对抑郁症状进行了评估。对患者进行了3年的中位随访，并通过查阅病历确定了室性心律失常的发生。结果：97例患者发生室性心律不齐，与经统计确定心律不齐的医学和人口统计学决定因素后的恐惧恐惧度高相关（比值比= 1.40; p = 0.012）。抑郁症状与恐惧症显着相关（r = 0.44，p <.001），还与室性心律不齐有关（几率= 1.40; p = .006）。与单独的抑郁或恐惧焦虑评分相比，抑郁和恐惧焦虑的复合预测室性心律失常的影响更大（优势比= 1.6、95％置信区间1.2-2.1，p = 0.002）。结论恐惧症和抑郁症状都可以预测CAD患者的室性心律失常，并且可能具有共同的预测室性心律失常的因素。

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