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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Chronic exposure to everyday discrimination and coronary artery calcification in African-American women: the SWAN Heart Study.
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Chronic exposure to everyday discrimination and coronary artery calcification in African-American women: the SWAN Heart Study.

机译：非洲裔美国妇女长期暴露于日常歧视和冠状动脉钙化：SWAN心脏研究。

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BACKGROUND: Emerging evidence suggests that exposure to discrimination may be associated with atherosclerosis in African-American women, although research in this area focused on short-term rather than chronic exposure to discriminatory events. METHODS: We examined the relationship between chronic exposure to multiple types of discrimination (self-reported and averaged over 5 years) and coronary artery calcification (CAC) in a sample of 181 middle-aged African-American women. Discrimination was assessed at each time point, and the presence/absence of CAC was assessed at the fifth annual follow-up examination by electron beam tomography. We hypothesized that chronic discrimination would be more strongly associated with CAC than recent discrimination and that racial/ethnic discrimination would be more strongly associated with CAC than other types of discrimination. RESULTS: Chronic exposure to discrimination was significantly associated with the presence of CAC in unadjusted logistic regression analyses (p = .007) and after adjustment for demographics (p = .01), standard cardiovascular risk factors (p = .02), and Body Mass Index (BMI) (p = .05). In contrast, recent discrimination was only marginally associated with the presence of CAC in both unadjusted (p = .06) and fully adjusted logistic regression models (p = .08). Persistent exposure to racial/ethnic discrimination was not more strongly associated with CAC compared with other types of discrimination in either unadjusted or adjusted models. CONCLUSION: Chronic exposure to discrimination may be an important risk factor for early coronary calcification in African-American women. This association appears to be driven by exposure to discrimination from multiple sources, rather than exposure to racial/ethnic discrimination alone.
机译：背景：新兴证据表明，受歧视的人群可能与非洲裔美国妇女的动脉粥样硬化有关，尽管该领域的研究重点是短期而非长期暴露于歧视性事件。方法：我们在181名中年非洲裔女性样本中检查了长期遭受多种歧视（自我报告且平均5年）的长期暴露与冠状动脉钙化（CAC）之间的关系。在每个时间点评估歧视，并在第五次年度随访检查中通过电子束断层扫描评估CAC的存在与否。我们假设，与最近的歧视相比，长期歧视与CAC的关联更紧密，与其他类型的歧视相比，种族/族裔歧视与CAC的关联更紧密。结果：在未经调整的逻辑回归分析（p = .007）中以及在调整了人口统计学特征（p = .01），标准的心血管危险因素（p = .02）和身体因素之后，长期受到歧视的暴露与CAC的存在显着相关。质量指数（BMI）（p = .05）。相比之下，在未经调整的（p = .06）和经过全面调整的logistic回归模型（p = .08）中，最近的歧视仅与CAC的存在相关。与未经校正或经过校正的模型中的其他类型的歧视相比，持续暴露于种族/族裔歧视与CAC的关联性不强。结论：长期暴露于歧视可能是非洲裔美国妇女早期冠脉钙化的重要危险因素。这种联系似乎是由于受到来自多种来源的歧视的影响，而不是仅仅受到种族/种族歧视的影响。

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