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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >A one-hour active coping stressor reduces small bowel transit time in healthy young adults.
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A one-hour active coping stressor reduces small bowel transit time in healthy young adults.

机译：一小时的主动应对压力源可以减少健康的年轻人的肠蠕动时间。

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摘要

OBJECTIVE: To examine the effect of a prolonged active coping stressor on the transit of a substance from the mouth through small intestine in normal human volunteers. METHOD: Twelve healthy undergraduate males were administered 10 g of the nonabsorbable carbohydrate lactulose in two experimental sessions. In normal individuals, lactulose produces hydrogen gas upon exposure to bacteria residing in the colon. Repeated measurements of breath hydrogen were obtained for 2 hours. In one session, subjects rested quietly for the 2-hour period. In the other counterbalanced session, subjects avoided mild electric shocks by playing videogames for the first hour. RESULTS: Stress produced a statistically and clinically significant reduction in mean transit time, from 79 to 55 minutes. The magnitude of stress-induced reduction in small bowel transit time was significantly correlated with change in an index of cardiac sympathetic activity, pulse transit time. CONCLUSIONS: A prolonged active coping stressor with minimal motor requirements produced a decrease in small bowel transit time comparable with that observed in several studies of the effects of physical exercise and in comparisons between normal controls and patients with diarrhea-predominant irritable bowel syndrome.
机译：目的：研究长期的主动应对应激源对正常人类志愿者从口腔通过小肠转移某种物质的影响。方法：十二个健康的大学生男性在两次实验中服用了10克不可吸收的碳水化合物乳果糖。在正常个体中，乳果糖暴露于结肠中的细菌会产生氢气。重复测量呼吸氢2小时。在一个阶段中，受试者安静地休息了2个小时。在另一个平衡的时段中，受试者通过在第一个小时玩电子游戏避免了轻微的电击。结果：压力在统计学上和临床上显着减少了平均运输时间，从79分钟缩短至55分钟。应激引起的小肠运输时间减少的幅度与心脏交感神经活动指数，脉冲运输时间的变化显着相关。结论：长时间的活动应对压力和最小的运动要求产生的肠蠕动时间减少，与体育锻炼效果的几项研究以及正常对照组和腹泻型肠易激综合征患者的比较研究中观察到的时间相当。

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