• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Generalized anxiety disorder and peptic ulcer disease among adults in the United States.
【24h】

Generalized anxiety disorder and peptic ulcer disease among adults in the United States.

机译：美国成年人中的广泛性焦虑症和消化性溃疡疾病。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: Previous research has suggested a link between chronic anxiety and peptic ulcer disease, though recent evidence documenting an infectious cause (Helicobacter pylori) for ulcer has led to doubt about this association. The goal of the current study was to determine the relationship between generalized anxiety disorder (GAD) and self-reported peptic ulcer disease (PUD) among adults in the community. METHODS: Data were drawn from the National Comorbidity Survey, a representative household survey of the adult population of the United States (N = 8098). Multivariate logistic regression analyses were used to determine the relationship between GAD and self-reported ulcer, controlling for differences in sociodemographic characteristics and psychiatric and medical comorbidity. RESULTS: GAD was associated with a significantly increased risk of self-reported PUD (odds ratio = 2.8, 95% confidence interval = 1.4-5.7; p =.0002) after adjusting for differences in sociodemographic characteristics, comorbid mental disorders, and physical morbidity. Further analyses revealed a dose-response relationship between number of GAD symptoms (odds ratio = 1.2, 95% confidence interval = 1.1-1.4; p =.001) and increased risk of self-reported PUD. CONCLUSIONS: These findings are consistent with and extend previous clinical and epidemiologic data, providing evidence of a dose-response relationship between GAD and self-reported PUD among adults in the general population. The mechanism of this association remains unknown. Future work investigating the relationship between onset of GAD and development of PUD in prospective, longitudinal, epidemiologic data with objective measures of physical health status and mental health may be useful in improving our understanding of this link.
机译：目的：尽管最近的证据表明溃疡的传染性原因（幽门螺杆菌）已引起人们对该关联的怀疑，但先前的研究表明慢性焦虑与消化性溃疡疾病之间存在联系。本研究的目的是确定社区成年人中广泛性焦虑症（GAD）与自我报告的消化性溃疡疾病（PUD）之间的关系。方法：数据来自全国合并症调查，该调查是美国成年人口的一项有代表性的家庭调查（N = 8098）。多元logistic回归分析用于确定GAD与自我报告的溃疡之间的关系，以控制社会人口统计学特征以及精神病和医学合并症的差异。结果：在调整了社会人口统计学特征，合并症，精神疾病和身体发病率的差异之后，GAD与自我报告的PUD风险显着增加相关（奇数比= 2.8，95％置信区间= 1.4-5.7; p = .0002） 。进一步的分析显示GAD症状数量之间的剂量反应关系（几率= 1.2，95％置信区间= 1.1-1.4; p = .001）和自我报告的PUD风险增加。结论：这些发现与先前的临床和流行病学数据相符并扩展了以前的临床和流行病学数据，为一般人群中成年人GAD与自我报告的PUD之间的剂量反应关系提供了证据。这种关联的机制仍然未知。未来的研究调查前瞻性，纵向，流行病学数据中GAD发病与PUD发生之间的关系，并以客观的身体健康状况和精神健康指标进行衡量，可能有助于增进我们对这一联系的理解。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号