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Associations of chronic stress burden, perceived stress, and traumatic stress with cardiovascular disease prevalence and risk factors in the hispanic community health study/study of latinos sociocultural ancillary study

机译:在西班牙裔社区健康研究/拉丁美洲人社会文化辅助研究中,慢性压力负担,感知压力和创伤压力与心血管疾病患病率和危险因素的关系

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OBJECTIVE: The current study examined multiple stress indicators (chronic, perceived, traumatic) in relation to prevalent coronary heart disease, stroke, and major cardiovascular disease (CVD) risk factors (i.e., diabetes, dyslipidemia, hypertension, and current smoking) in the multisite Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study (2010-2011). METHODS: Participants were 5313 men and women 18 to 74 years old, representing diverse Hispanic/Latino ethnic backgrounds, who underwent a comprehensive baseline clinical examination and sociocultural examination with measures of stress. RESULTS: Chronic stress burden was related to a higher prevalence of coronary heart disease after adjusting for sociodemographic, behavioral, and biological risk factors (odds ratio [OR; 95% confidence interval], 1.22 [1.10-1.36]) and related to stroke prevalence in the model adjusted for demographic and behavioral factors (OR [95% confidence interval], 1.26 [1.03-1.55]). Chronic stress was also related to a higher prevalence of diabetes (OR = 1.20 [1.11-1.31]) and hypertension (OR = 1.10 [1.02-1.19]) in individuals free from CVD (n = 4926). Perceived stress (OR = 1.03 [1.01-1.05]) and traumatic stress (OR = 1.15 [1.05-1.26]) were associated with a higher prevalence of smoking. Participants who reported a greater number of lifetime traumatic events also unexpectedly showed a lower prevalence of diabetes (OR = 0.89 [0.83-0.97]) and hypertension (OR = 0.88 [0.82-0.93]). Effects were largely consistent across age and sex groups. CONCLUSIONS: The study underscores the advantages of examining multiple indicators of stress in relation to health because the direction and consistency of associations may vary across distinct stress conceptualizations. In addition, the study suggests that chronic stress is related to higher CVD risk and prevalence in Hispanics/Latinos, the largest US ethnic minority group.
机译:目的:本研究检查了与广泛的冠心病,中风和主要心血管疾病(CVD)危险因素(即糖尿病,血脂异常,高血压和当前吸烟)有关的多种压力指标(慢性,感知,创伤)。多站点西班牙裔社区健康研究/拉丁裔社会文化辅助研究研究(2010-2011年)。方法:参与者为5313名年龄在18至74岁之间的男性和女性,分别代表不同的西班牙裔/拉丁美洲裔背景,他们接受了全面的基线临床检查和社会文化检查,并对压力进行了测量。结果:在调整了社会人口统计学,行为和生物危险因素后,慢性应激负担与冠心病的患病率较高(几率[OR; 95%置信区间],1.22 [1.10-1.36])和中风患病率有关在模型中针对人口因素和行为因素进行了调整(OR [95%置信区间],1.26 [1.03-1.55])。在没有CVD的个体中,慢性应激还与较高的糖尿病患病率(OR = 1.20 [1.11-1.31])和高血压(OR = 1.10 [1.02-1.19])(n = 4926)。感知压力(OR = 1.03 [1.01-1.05])和创伤性压力(OR = 1.15 [1.05-1.26])与吸烟率较高相关。参加者报告了一生中发生的大量创伤事件也出乎意料地显示出糖尿病(OR = 0.89 [0.83-0.97])和高血压(OR = 0.88 [0.82-0.93])的患病率较低。跨年龄和性别群体的效果在很大程度上是一致的。结论:本研究强调检查与健康相关的多种压力指标的优势,因为协会的方向和一致性在不同的压力概念中可能会有所不同。此外,研究表明,慢性应激与美国最大的少数族裔西班牙裔/拉丁裔患较高的CVD风险和患病率有关。

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