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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Hostility and fasting glucose in African American women.
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Hostility and fasting glucose in African American women.

机译：非洲裔美国女性的敌意和空腹血糖。

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OBJECTIVE: To examine whether the relationship of hostility (HOST) to fasting glucose indices is moderated by sex and race. HOST has been associated with abnormalities in glucose metabolism. Prior studies suggested that this association may be more prevalent in women and in African American (AA) individuals. METHODS: A total of 565 healthy AA and white (W) men and women (mean age = 33 +/- 6 years) were assessed. HOST was measured by the 27-item version of the Cook Medley HOST Scale. The moderating effects of sex and race were evaluated for the associations of HOST to fasting glucose, insulin, and insulin sensitivity (HOMA-IR). RESULTS: Analysis showed a moderating effect of sex and race on the association of HOST to fasting glucose (p = .03), but not for insulin (p = .12). Analysis of HOMA-IR revealed a trend (p = .06) for the interaction. Stratified analyses by race and sex revealed a positive association between HOST and fasting glucose only in AA women, which remained significant after controlling for age and body mass index. CONCLUSION: A relationship between HOST and fasting glucose was evident in AA women only, a group that has twice the risk of developing Type 2 diabetes compared with W women. Further studies are needed to elucidate the mechanisms by which HOST may affect glucose metabolism in AA women.
机译：目的：研究敌对性（HOST）与空腹血糖指数的关系是否受到性别和种族的调节。 HOST与葡萄糖代谢异常有关。先前的研究表明，这种关联可能在女性和非裔美国人（AA）个体中更为普遍。方法：共评估了565名健康AA和白人（W）男女（平均年龄= 33 +/- 6岁）。用27个项目的Cook Medley HOST量表测量HOST。对于HOST与空腹血糖，胰岛素和胰岛素敏感性（HOMA-IR）的关联，评估了性别和种族的调节作用。结果：分析表明，性别和种族对HOST与空腹血糖的相关性有调节作用（p = .03），但对胰岛素没有影响（p = .12）。 HOMA-IR的分析显示了相互作用的趋势（p = .06）。按种族和性别进行的分层分析显示，只有AA妇女的HOST与空腹血糖之间呈正相关，在控制了年龄和体重指数后，这一关系仍然很明显。结论：仅在AA妇女中，HOST和空腹血糖之间存在相关性，与W妇女相比，该妇女罹患2型糖尿病的风险是其两倍。需要进一步的研究来阐明HOST可能影响机管局妇女的葡萄糖代谢的机制。

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