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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Depressive symptoms favor abundant growth of salivary lactobacilli.
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Depressive symptoms favor abundant growth of salivary lactobacilli.

机译：抑郁症状有利于唾液乳酸杆菌的大量生长。

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OBJECTIVE: The purpose was to study the growth of lactobacilli in subjects with depressive symptoms in the total 55-year-old population of Oulu (a medium-sized town in Finland); 780 people participated. METHODS: The dental examination included measurements of salivary lactobacillus growth with the Dentocult-LB method; measurements of salivary flow rate, pH, and buffering capacity; and assessment of oral health status. Depressive symptoms were determined with the Zung Self-Rating Depression Scale (ZSDS). Participants were also asked about their health, medication, smoking, and dietary habits. RESULTS: The prevalence of high lactobacillus counts (> or =100,000 CFU/ml) was 22% among women and 31% among men (p = .02). Thirty-seven percent of the subjects with a high rate of depressive symptoms (ZSDS score of > or = 40) and 23% of those with an ZSDS score of < or = 39 had high counts of lactobacilli (p = .003). A logistic regression analysis with improvement of goodness of fit was made to confirm the relation between abundant lactobacilli and a high rate of depressive symptoms. After the confounding factors had been added stepwise into the logistic regression model, depressive symptoms were still significantly associated with abundant lactobacillus growth. CONCLUSIONS: The association between high lactobacillus counts and depressive symptoms suggests that depressed subjects are at risk of having caries and possibly other dental diseases that should be recognized in the treatment of these patients.
机译：目的：研究奥卢（芬兰中型城镇）55岁总人口中抑郁症状患者乳杆菌的生长情况。 780人参加了。方法：牙科检查包括用Dentocult-LB法测量唾液乳酸杆菌的生长;测量唾液流速，pH和缓冲能力;和评估口腔健康状况。使用Zung自评抑郁量表（ZSDS）确定抑郁症状。还向参与者询问了他们的健康状况，药物，吸烟和饮食习惯。结果：高乳酸菌计数（>或= 100,000 CFU / ml）的患病率在女性中为22％，在男性中为31％（p = .02）。抑郁症状发生率高（ZSDS得分>或= 40）的受试者中有37％，ZSDS得分<或= 39的受试者中有23％的乳杆菌数量很高（p = 0.003）。进行了对数拟合度改善的逻辑回归分析，以确认丰富的乳酸杆菌与高抑郁症状发生率之间的关系。在将混杂因素逐步添加到逻辑回归模型中之后，抑郁症状仍与大量乳酸菌生长显着相关。结论高乳酸菌计数与抑郁症状之间的相关性表明，抑郁症患者有患龋齿和可能在治疗这些患者中应认识的其他牙科疾病的风险。

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