首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Relationship between clinical pain complaints and pain sensitivity in patients with depression and panic disorder.
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Relationship between clinical pain complaints and pain sensitivity in patients with depression and panic disorder.

机译:抑郁症和恐慌症患者的临床疼痛主诉与疼痛敏感性之间的关系。

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OBJECTIVE: There is evidence that depression and panic disorder are both associated with an increased frequency of clinical pain complaints. A change in pain sensitivity is alleged to be involved in this phenomenon. However, few studies have assessed clinical pain complaints and pain sensitivity in the same group of patients. METHODS: Thirteen patients with a major depressive disorder, 13 patients with a panic disorder (diagnoses based on the Diagnostic and Statistical Manual of Mental Disorders, fourth edition), and 13 healthy control subjects were investigated. None of the subjects were taking medications. Body maps were used to measure the number of painful sites as well as the intensity and unpleasantness of pain complaints in the previous 6 months. Furthermore, pain thresholds for pressure, cold, and heat were assessed at the forearm or hand. RESULTS: Patients with depression and panic disorder had significantly more frequent, more intense, and more unpleasant pain complaints than healthy control subjects. Despite this similarity, patients with depression had significantly higher pain thresholds than patients with panic disorder in two (pressure and cold) of three stimulus modalities and significantly higher pressure pain thresholds than the healthy control subjects. There were no differences between the pain thresholds of patients with panic disorder and healthy control subjects. The correlations between clinical pain measures and pain thresholds were generally weak. CONCLUSIONS: These findings suggest that the clinical pain complaints of patients with depression and panic disorder cannot simply be explained by changes in pain sensitivity.
机译:目的:有证据表明,抑郁症和恐慌症均与临床疼痛投诉频率增加有关。据称这种现象与疼痛敏感性的改变有关。但是,很少有研究评估同一组患者的临床疼痛主诉和疼痛敏感性。方法:调查了13名重度抑郁症患者,13例恐慌症患者(根据《精神疾病诊断和统计手册》(第四版)进行的诊断)和13例健康对照者。没有受试者正在服药。人体图被用来测量疼痛部位的数量以及在过去6个月中疼痛症状的强度和不愉快程度。此外,在前臂或手上评估了压力,寒冷和高温的疼痛阈值。结果:与健康对照组相比,抑郁症和恐慌症患者的疼痛症状明显更频繁,更强烈,更不愉快。尽管有这种相似性,但在三种刺激方式(压力和感冒)的两种(抑郁和感冒)中,抑郁症患者的疼痛阈值显着高于惊慌症患者,而压力阈值也显着高于健康对照组。恐慌症患者的疼痛阈值与健康对照者之间没有差异。临床疼痛措施和疼痛阈值之间的相关性通常较弱。结论:这些发现表明,抑郁症和恐慌症患者的临床疼痛主诉不能简单地通过疼痛敏感性的变化来解释。

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