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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Family chaos and adolescent inflammatory profiles: The moderating role of socioeconomic status
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Family chaos and adolescent inflammatory profiles: The moderating role of socioeconomic status

机译：家庭混乱和青少年炎症状况：社会经济地位的调节作用

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摘要

OBJECTIVE: To test whether family chaos influences adolescents' inflammatory profiles and whether adolescents from low socioeconomic status (SES) environments are at higher risk for experiencing adverse inflammatory profiles from living in chaotic family environments. METHODS: A total of 244 families with an adolescent aged 13 to 16 years participated. Parents completed measures of family SES and family chaos. Both systemic inflammation and stimulated proinflammatory cytokine production in response to bacterial challenge were assessed in adolescents. RESULTS: Our results suggest that SES moderates the detrimental effect of family chaos on systemic inflammation and interleukin-6 (B = -0.010, standard error [SE] = 0.004, p = .026), but not C-reactive protein (B = 0.009, SE = 0.006, p = .11), and on stimulated proinflammatory cytokine production (B = -0.098, SE = 0.044, p = .026) in adolescents, such that a chaotic family environment is positively associated with greater systemic inflammation and greater stimulated proinflammatory cytokine production in adolescents as family SES declines. CONCLUSIONS: These findings indicate that living in chaotic family environments places youth who may be vulnerable based on socioeconomic factors at a potentially higher risk for inflammation-related diseases.
机译：目的：测试家庭混乱是否会影响青少年的炎症状况，以及来自低社会经济地位（SES）环境的青少年在生活在混乱的家庭环境中遭受不良炎症状况的风险是否更高。方法：共有244个13至16岁青少年家庭参加。父母完成了对家庭SES和家庭混乱的评估。在青少年中评估了针对细菌攻击的全身性炎症和刺激性促炎性细胞因子的产生。结果：我们的结果表明，SES减轻了家庭混乱对全身性炎症和白细胞介素6的有害影响（B = -0.010，标准误[SE] = 0.004，p = .026），但没有C反应蛋白（B = 0.009，SE = 0.006，p = .11），并在青少年中刺激促炎性细胞因子生成（B = -0.098，SE = 0.044，p = .026），因此混乱的家庭环境与更大的全身性炎症呈正相关。随着家庭SES减少，青少年刺激性促炎细胞因子的产生增加。结论：这些发现表明，生活在混乱的家庭环境中，可能因社会经济因素而容易受到伤害的青年处于与炎症相关疾病的潜在更高风险中。

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