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The Prevalence of Bipolar Disorder in Primary Care Patients With Depression or Other Psychiatric Complaints: A Systematic Review

机译:患有抑郁症或其他精神疾病投诉的初级保健患者中双相情感障碍的患病率:系统评价

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Background: Bipolar disorder prevalence in primary care patients with depression or other psychiatric complaints has been measured in several studies but has not been systematically reviewed. Objective: To systematically review studies measuring bipolar disorder prevalence in primary care patients with depression or other psychiatric complaints. Methods: We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method in January 2013. We searched 7 databases using a comprehensive list of search terms. Included articles had a sample size of 200 patients or more and assessed bipolar disorder using a structured clinical interview or bipolar screening questionnaire in adult primary care patients with a prior diagnosis of depression or had an alternate psychiatric complaint. Results: Our search yielded 5595 unique records. Seven cross-sectional studies met our inclusion criteria. The percentage of primary care patients with bipolar disorder was measured in 4 studies of patients with depression, 1 study of patients with trauma exposure, 1 study of patients with any psychiatric complaint, and 1 study of patients with medically unexplained symptoms. The percentage of patients with bipolar disorder ranged from 3.4%-9% in studies using structured clinical interviews and from 20.9%-30.8% in studies using screening measures. Conclusions: Bipolar disorder likely occurs in 3%-9% of primary care patients with depression, a trauma exposure, medically unexplained symptoms, or a psychiatric complaint. Screening measures used for bipolar disorder detection overestimate the occurrence of bipolar disorder in primary care owing to false positives.
机译:背景:抑郁症或其他精神疾病主治患者的双相情感障碍患病率已在多项研究中进行了测量,但尚未得到系统的审查。目的:系统地评估测量抑郁症或其他精神疾病主治患者双相情感障碍患病率的研究。方法:我们于2013年1月使用“系统评价和荟萃分析的首选报告项目”进行了系统评价。我们使用全面的搜索词列表搜索了7个数据库。纳入的文章具有200名或更多患者的样本量,并使用结构化临床访谈或双相筛查问卷评估了患有抑郁症或有其他精神疾病主诉的成年初级保健患者的双相情感障碍。结果:我们的搜索产生了5595条独特的记录。七项横断面研究符合我们的纳入标准。在4项抑郁症患者,1项创伤暴露患者,1项精神病患者的研究以及1项医学原因不明的患者的研究中,测量了躁郁症初级保健患者的百分比。在进行结构性临床访谈的研究中,躁郁症患者的百分比在3.4%-9%之间,而在使用筛查手段的研究中,则为20.9%-30.8%。结论:躁郁症,外伤暴露,医学上无法解释的症状或精神病主诉的初级保健患者中,可能有3%-9%发生双相情感障碍。用于双相情感障碍检测的筛查措施由于误报而高估了初级保健中双相情感障碍的发生。

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