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首页> 外文期刊>Psychosomatics >Novelty-seeking in Parkinson's disease after deep brain stimulation of the subthalamic nucleus: a case-control study.
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Novelty-seeking in Parkinson's disease after deep brain stimulation of the subthalamic nucleus: a case-control study.

机译：丘脑底核深部脑刺激后在帕金森氏病中寻求新颖性的病例对照研究。

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BACKGROUND: The prevalence of psychiatric comorbidity in Parkinson's disease (PD) is about 50%. OBJECTIVE: The authors investigated differences among PD patients treated by deep brain stimulation (DBS), by drugs alone (noDBS), and healthy control subjects. METHOD: Samples of 22 subjects in each group were assessed with the Temperament and Character Inventory (TCI) and Hamilton scales for anxiety and depression (Ham-A and Ham-D). RESULTS: Higher scores emerged on two Novelty-Seeking subscales in PD-DBS patients. Ham-A and Ham-D scores were lower in PD-DBS patients than in PD-noDBS patients and control subjects. Rigidity and non-impulsiveness were lower in PD-DBS than in PD-noDBS patients. CONCLUSION: Further studies should investigate whether or not these changes in personality are a consequence of the motor and depression improvement after DBS.
机译：背景：帕金森氏病（PD）中精神病合并症的患病率约为50％。目的：作者调查了通过深部脑刺激（DBS），仅使用药物（noDBS）治疗的PD患者与健康对照者之间的差异。方法：用气质和性格量表（TCI）和汉密尔顿量表（Ham-A和Ham-D）评估每组22名受试者的样本。结果：PD-DBS患者在两个“寻求新颖性”量表上得分更高。 PD-DBS患者的Ham-A和Ham-D得分低于PD-noDBS患者和对照受试者。 PD-DBS患者的刚性和非冲动性低于PD-noDBS患者。结论：进一步的研究应调查这些人格变化是否是DBS后运动和抑郁改善的结果。

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