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首页> 外文期刊>Psychosomatics >Intravenous lipid emulsion-associated catatonia, thrombocytopenia, and leukopenia: a case report and the role of NMDA receptor.
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Intravenous lipid emulsion-associated catatonia, thrombocytopenia, and leukopenia: a case report and the role of NMDA receptor.

机译：静脉脂质乳剂相关的紧张症，血小板减少症和白细胞减少症：一例病例报道和NMDA受体的作用。

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摘要

Intravenous lipid emulsions (ILEs) are used as a high-calorie nutritional source and to prevent essential fatty acid deficiency in patients who are unable to obtain adequate enteral nourishment. Over the last few years, mounting evidence supports ILE as a potentially beneficial antidote, not only in local anesthetic toxicity but also in cardiovascular collapse or central nervous system depression secondary to overdose of highly lipophilic medications. The overall rate of adverse effects (AEs) associated with ILEs is low, though they may include hypertriglyc-eridemia, acute pancreatitis, cholestasis, and increased risk of infection. Hematological AEs of ILEs are relatively rare, and almost all of the cases occur in pediatric patients following long-term exposure.
机译：静脉脂质乳剂（ILE）用作高热量营养来源，可防止无法获得足够肠内营养的患者出现必需脂肪酸缺乏症。在过去的几年中，越来越多的证据支持ILE作为潜在的有益解毒剂，不仅在局部麻醉药毒性方面，而且在因高脂溶性药物过量引起的心血管衰竭或中枢神经系统抑制中也是如此。与ILE相关的不良反应（AE）总体发生率较低，尽管它们可能包括高甘油三酯血症，急性胰腺炎，胆汁淤积和感染风险增加。 ILE的血液学不良事件相对较少，长期接触后，几乎所有病例都发生在儿科患者中。

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