Lamotrigine-Associated Rash and Blood Dyscrasias in a Methadone-Treatment Patient With Hepatitis C

Shirley Alleyne; Adekola Alao; Steven L. Batki

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Lamotrigine-Associated Rash and Blood Dyscrasias in a Methadone-Treatment Patient With Hepatitis C

机译：美沙酮治疗丙型肝炎患者的拉莫三嗪相关性皮疹和血液异常

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Individuals with hepatitis C infection and those in metha-done treatment are known to have high rates of mood disorders. Lamotrigine is an anticonvulsant approved by the FDA for the treatment of bipolar disorder, particularly for bipolar depression. Rash has been reported as the most frequent adverse effect of lamotrigine, whereas blood dyscrasias have been noted rarely.1 We report the occurrence of rash, thrombocytopenia, and neutropenia associated with lamotrigine in a methadone-treatment patient with hepatitis C infection.

机译：已知患有丙型肝炎感染的人和接受甲乙酮治疗的人的情绪障碍发生率很高。拉莫三嗪是FDA批准的抗惊厥药，用于治疗躁郁症，尤其是躁郁症。据报道，皮疹是拉莫三嗪最常见的不良反应，而鲜少发现血液异常。1我们报道了在接受美沙酮治疗的丙型肝炎患者中发生了与拉莫三嗪有关的皮疹，血小板减少和中性粒细胞减少症。

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《Psychosomatics》 |2006年第3期|共1页
作者
Shirley Alleyne; Adekola Alao; Steven L. Batki;
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正文语种 eng
中图分类医学心理学、病理心理学;
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1. Lamotrigine-Associated Rash and Blood Dyscrasias in a Methadone-Treatment Patient With Hepatitis C [J] . Shirley Alleyne, Adekola Alao, Steven L. Batki Psychosomatics . 2006,第3期

机译：美沙酮治疗丙型肝炎患者的拉莫三嗪相关性皮疹和血液异常
2. Rash in Patients after T-Cell-Depleted Peripheral Blood Stem Cell Transplantation: Eosinophilia and Pruritus Do Not Distinguish Acute Graft-Versus-Host Disease from Drug Rash [J] . Klager Skylar A., Devlin Sean M., Hannum Margaret, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：T细胞耗尽外周血干细胞移植后患者皮疹：嗜酸性粒细胞和瘙痒症不区分急性接枝与宿主疾病免受药疹
3. The Prevalence of Plasma Cell Dyscrasia in Hepatitis C Patients [J] . Dies David F., Davis Jeremy P. Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2017,第Suppla1期

机译：丙型肝炎患者血浆细胞多塞血症的患病率
4. The Influence of Hepatocyte Growth-Promoting Factors Combined with Gongying Yinchen Soup for Depression in Patients with Fulminant Hepatitis Peripheral Blood T Lymphocyte Subsets and Liver Function [C] . Liping Wu, Junfeng Gao, Xinguo Zhao, International symposium on IT in medicine and education . 2014

机译：肝细胞促生长因子联合巩膜饮汤对恶性肝炎患者外周血T淋巴细胞亚群和肝功能下降的影响
5. The S.H.I.V.E.R.I.N.G. Trials: A Novel Vaccine Strategy and Analysis of Serologic Durability in Patients with Plasma Cell Dyscrasias [D] . Duffy, Eamon. 2018

机译：s.h.i.v.e.r.i.n.g.试验：一种新型疫苗策略和血浆细胞缺陷患者血清耐久性分析
6. Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia [O] . Jessica Foster, John Lally, Victoria Bell, 2017

机译：氯氮平相关血液功能异常的前三例患者成功接受氯氮平再挑战
7. Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia [O] . Foster* Jessica, Lally* John, Bell Victoria, 2017

机译：氯氮平相关血液功能异常的前三例患者成功接受氯氮平再挑战

Lamotrigine-Associated Rash and Blood Dyscrasias in a Methadone-Treatment Patient With Hepatitis C

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