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Somatic symptoms for diagnosing major depression in cancer patients.

机译:用于诊断癌症患者严重抑郁的躯体症状。

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Diagnosing depression in cancer patients has been challenging because the diagnostic criteria include somatic symptoms frequently attributed to the cancer itself or its treatment. However, few studies have explored how to appropriately deal with individual somatic symptoms. The authors used data from 220 cancer patients with major depression to examine the intercorrelations among the DSM-IV somatic and nonsomatic symptom criteria as well as whether the presence of an individual somatic symptom could discriminate the severity of major depression. Appetite changes and a diminished ability to think were positively associated with anhedonia. Sleep disturbance and fatigue were not significantly associated with nonsomatic symptoms. These associations were consistent after adjusting for physical functioning and pain. Only patients with appetite changes showed a higher severity of depression. These results suggest that individual somatic symptoms differ in nature and that appetite-related symptoms and a diminished ability to think may be useful for diagnosing depression in cancer patients, whereas sleep disturbances and fatigue may not be as useful.
机译:诊断癌症患者的抑郁症一直具有挑战性,因为诊断标准包括经常归因于癌症本身或其治疗的躯体症状。但是,很少有研究探索如何适当地处理个体的躯体症状。作者使用来自220名患有严重抑郁症的癌症患者的数据来检查DSM-IV躯体和非躯体症状标准之间的相互关系,以及单个躯体症状的存在是否可以区分严重抑郁症的严重程度。食欲改变和思维能力下降与快感缺乏症呈正相关。睡眠障碍和疲劳与非躯体症状无明显关联。调整身体机能和疼痛后,这些关联是一致的。只有食欲改变的患者表现出更高的抑郁程度。这些结果表明,个体躯体症状的性质不同,与食欲有关的症状和思维能力的下降可能有助于诊断癌症患者的抑郁症,而睡眠障碍和疲劳可能没有作用。

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