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首页> 外文期刊>Ultrasound in Medicine and Biology >Estimation of wrist fracture load using phalangeal speed of sound: an in vitro study.
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Estimation of wrist fracture load using phalangeal speed of sound: an in vitro study.

机译：使用指骨声速估算腕部骨折负荷：一项体外研究。

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This study aimed to evaluate the ability of speed of sound (SOS) measured at the phalanges to estimate simulated wrist fracture load and stress. SOS was measured along the proximal phalanges of the second, third and fourth fingers using an ultrasound (US) system operating in axial transmission mode. The bone mineral density (BMD) of the radius and the phalanges was also measured with quantitative computed tomography (QCT) and dual x-ray absorptiometry (DXA), and the combined cortical thickness (CCT) of the phalanges was measured from hand radiographs. After the measurements were completed, the radius was excised from the cadaver, embedded in polymethylmethacrylate and tested to failure on a servohydraulic testing machine. The configuration of the radius was chosen to simulate a fall onto the hand. Linear regression analysis showed a highly significant correlation between SOS (r = 0.76-0.94, p < 0.001), CCT (r = 0.86-0.90, p < 0.001) and BMD (r = 0.92-0.96, p < 0.0001) in the three proximal phalanges measured. SOS, BMD and CCT were significant predictors of fracture load (r = 0.60-0.69, p < 0.03) and stress (r = 0.65-0.77, p < 0.02). Cortical area and bone mineral content (BMC) of the radius were consistently higher predictors of fracture load (r = 0.76-0.82, p < 0.01 for area and r = 0.78-0.88, p < 0.01 for BMC) than BMD. The correlation of BMC and area was poorer with fracture stress. In a step-wise regression analysis using both phalangeal BMD and SOS, only SOS remained a significant predictor of fracture stress. In forward stepwise regression analysis, both cortical area and SOS were entered into the regression model to estimate fracture load. Only SOS remained significant in the model for estimating fracture stress. Phalangeal BMD was only entered in the combined model with the cortical area at the 4% site (r = 0.84, p = 0.002). Phalangeal SOS is a useful parameter in the assessment of bone status of the radius.
机译：这项研究旨在评估在指骨处测量的声速（SOS）的能力，以估计模拟的腕部骨折负荷和应力。使用在轴向传输模式下运行的超声（US）系统，沿着第二，第三和第四根手指的近指骨测量SOS。 quantitative骨和指骨的骨矿物质密度（BMD）也通过定量计算机断层扫描（QCT）和双X线吸收法（DXA）进行了测量，并且指骨的皮质总厚度（CCT）通过手部X射线照片进行了测量。测量完成后，从尸体上切下半径，将其嵌入聚甲基丙烯酸甲酯中，并在伺服液压测试机上测试其是否失效。选择半径的形状以模拟掉落到手上。线性回归分析显示这三个方面的SOS（r = 0.76-0.94，p <0.001），CCT（r = 0.86-0.90，p <0.001）和BMD（r = 0.92-0.96，p <0.0001）之间具有高度显着的相关性测量近端指骨。 SOS，BMD和CCT是骨折负荷（r = 0.60-0.69，p <0.03）和应力（r = 0.65-0.77，p <0.02）的重要预测指标。 radius骨的皮质面积和骨矿物质含量（BMC）始终是BMD更高的骨折负荷预测因子（r = 0.76-0.82，p <0.01面积和r = 0.78-0.88，p <0.01）。骨折应力与BMC和面积的相关性较差。在使用指骨BMD和SOS进行的逐步回归分析中，只有SOS仍然是骨折应力的重要预测指标。在正向逐步回归分析中，将皮质面积和SOS都输入到回归模型中以估计骨折负荷。在估算断裂应力的模型中，只有SOS仍然很重要。仅在皮层面积在4％的位点（r = 0.84，p = 0.002）的组合模型中输入了八角膜BMD。 hal骨SOS是评估the骨状态的有用参数。

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