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首页> 外文期刊>Ultrasound in Medicine and Biology >Ultrasonic observation of blood disturbance in a stenosed tube: effects of flow acceleration and turbulence downstream.
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Ultrasonic observation of blood disturbance in a stenosed tube: effects of flow acceleration and turbulence downstream.

机译：超声观察狭窄管中血液干扰：下游流动加速和湍流的影响。

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摘要

Red blood cell (RBC) aggregation is known to be highly dependent on hemodynamic parameters such as shear rate, flow turbulence and flow acceleration under pulsatile flow. The effects of all three hemodynamic parameters on RBC aggregation and echogenicity of porcine whole blood were investigated downstream of an eccentric stenosis in a mock flow loop using B-mode images with Doppler spectrograms of a commercial ultrasonic system. A hyperechoic parabolic profile appeared downstream during flow acceleration, yielding another piece of evidence suggesting that the enhancement of rouleaux formation may be caused by flow acceleration. It was also found that echogenicity increased locally at a distance of three tube diameters downstream from the stenosis. The local increase of echogenicity is thought to be mainly due to flow turbulence. The hypoechoic "black hole" was also seen at the center of the tube downstream of the stenosis where blood flow was disturbed, and this may be caused by the compound effect of flow turbulence and shear rate.
机译：众所周知，红细胞（RBC）聚集高度依赖于血流动力学参数，例如剪切速率，流动湍流和脉动血流下的血流加速度。使用B型图像和商用超声系统的多普勒频谱图，在模拟流动回路中研究了偏心狭窄下游所有三个血液动力学参数对猪全血RBC聚集和回声的影响。高回声的抛物线轮廓在流动加速过程中出现在下游，这产生了另一条证据，表明轮流形成的增强可能是由流动加速引起的。还发现回声性在狭窄下游的三个管直径的距离处局部增加。回声的局部增加被认为主要是由于湍流引起的。低回声的“黑洞”也出现在狭窄下游的管中心，血液流动受到干扰，这可能是由于湍流和剪切速率的复合作用所致。

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