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首页> 外文期刊>Ultrasound in Medicine and Biology >Simultaneous ultrasound assessment of brachial artery shear stimulus and flow-mediated dilation during reactive hyperemia.
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Simultaneous ultrasound assessment of brachial artery shear stimulus and flow-mediated dilation during reactive hyperemia.

机译：反应性充血期间同时超声评估肱动脉剪切刺激和血流介导的扩张。

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摘要

In flow-mediated dilation (FMD) studies, brachial artery diameter changes due to reactive hyperaemia are typically measured through manual or automatic analysis of high resolution B-mode images while the stimulus of diameter change, i.e., the flow change, is qualitatively estimated by measuring the mean velocity in the vessel and assuming a parabolic velocity profile. This article describes an experimental approach to simultaneously measure the wall shear rate (WSR) and the diameter variations, through multigate spectral Doppler and B-mode image processing, respectively. By using an ultrasound advanced open platform (ULA-OP), experimental results from the brachial arteries of 15 presumed healthy volunteers have been obtained. The mean increments during reflow against baseline were 105% +/- 22% for the peak WSR and 8% +/- 3% for the FMD. The mean time interval between the WSR peak and the beginning of plateau of diameter waveform was 38 +/- 8 s. The results confirm that in young healthy subjects the postischemic vasodilation of brachial artery is largely correlated to the WSR increase.
机译：在流量介导的扩张（FMD）研究中，由于反应性充血引起的肱动脉直径变化通常通过对高分辨率B型图像的手动或自动分析来测量，而直径变化的刺激（即流量变化）可通过测量容器中的平均速度并假设抛物线速度曲线。本文介绍了一种通过多门频谱多普勒和B模式图像处理同时测量壁面剪切速率（WSR）和直径变化的实验方法。通过使用超声先进的开放平台（ULA-OP），从15位假定健康志愿者的肱动脉中获得了实验结果。相对于基线，回流期间的平均增量对于峰值WSR为105％+/- 22％，对于FMD为8％+/- 3％。 WSR峰值与直径波形的平稳开始之间的平均时间间隔为38 +/- 8 s。结果证实，在年轻健康的受试者中，肱动脉缺血后血管舒张与WSR升高很大程度上相关。

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