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首页> 外文期刊>Ultrasound in Medicine and Biology >The Effect of Vasospasm on Cerebral Perfusion: A Colour Duplex Study of the Extra- and Intracranial Cerebral Arteries
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The Effect of Vasospasm on Cerebral Perfusion: A Colour Duplex Study of the Extra- and Intracranial Cerebral Arteries

机译：血管痉挛对脑灌注的影响：颅外和颅内动脉的彩色双工研究。

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摘要

To assess whether middle cerebral artery (MCA) vasospasm reduces the flow volume in the corresponding extracranial internal carotid artery (ICA) or global cerebral blood flow volume (CBFV) in subarachnoid haemorrhage (SAH) patients, a colour duplex ultrasound study of the intra- and extracranial cerebral arteries was performed. MCA vasospasm was defined as a time-averaged maximum flow velocity (TAMX) exceeding 120 cm/s. ICA flow volumes and CBFV, were compared in each patient at maximum TAMX recorded in one MCA (" maximum-vasospasm" ) and when TAMX in the same vessel was closest to mean reference values (" no-vasospasm" ). Additionally, the CBFV course during the first 3 weeks after SAH was evaluated longitudinally. Data from age- and gender-matched healthy test persons served as control. In 28 patients with MCA vasospasm, 337 measurements were completed. Global CBFV was significantly reduced starting from day 3 after SAH. ICA flow volumes and CBFV were not different when comparing at " maximum-vasospasm" and " no-vasospasm". Compared with the control group, both were lower at either condition. Thus, in SAH patients, vasospasm even severe, in general does not further diminish ICA flow volumes and global CBFV, which are reduced already before the onset of vasospasm.
机译：为了评估蛛网膜下腔出血（SAH）患者的大脑中动脉（MCA）血管痉挛是减少相应的颅外颈内动脉（ICA）的流量还是总体脑血流量（CBFV），一项彩色双并进行颅外脑动脉。 MCA血管痉挛定义为超过120 cm / s的时间平均最大流速（TAMX）。比较每位患者在一个MCA中记录的最大TAMX时的ICA流量和CBFV（“最大血管痉挛”），并且同一血管中的TAMX最接近平均参考值（“无血管痉挛”）。另外，纵向评估了SAH后头3周内的CBFV进程。来自年龄和性别匹配的健康测试人员的数据作为对照。在28例MCA血管痉挛患者中，完成了337次测量。从SAH后的第3天开始，全球CBFV显着降低。在“最大血管痉挛”和“无血管痉挛”进行比较时，ICA流量和CBFV并无差异。与对照组相比，在任何一种情况下两者均较低。因此，在SAH患者中，血管痉挛甚至是严重的，通常不会进一步减少ICA流量和整体CBFV，而在血管痉挛发作之前，ICA流量和整体CBFV已经降低。

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