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Assessment of spectral doppler in preclinical ultrasound using a small-size rotating phantom

机译:使用小型旋转体模评估临床前超声中的频谱多普勒

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Preclinical ultrasound scanners are used to measure blood flow in small animals, but the potential errors in blood velocity measurements have not been quantified. This investigation rectifies this omission through the design and use of phantoms and evaluation of measurement errors for a preclinical ultrasound system (Vevo 770, Visualsonics, Toronto, ON, Canada). A ray model of geometric spectral broadening was used to predict velocity errors. A small-scale rotating phantom, made from tissue-mimicking material, was developed. True and Doppler-measured maximum velocities of the moving targets were compared over a range of angles from 10° to 80°. Results indicate that the maximum velocity was overestimated by up to 158% by spectral Doppler. There was good agreement (<10%) between theoretical velocity errors and measured errors for beam-target angles of 50°-80°. However, for angles of 10°-40°, the agreement was not as good (>50%). The phantom is capable of validating the performance of blood velocity measurement in preclinical ultrasound.
机译:临床前超声扫描仪用于测量小动物的血流,但尚未量化血流速度测量中的潜在误差。这项研究通过设计和使用人体模型以及评估临床前超声系统(加拿大安大略省多伦多市的Vevo 770,Visualsonics,Vevo 770)来纠正这种遗漏。几何光谱展宽的射线模型用于预测速度误差。开发了一种由模仿组织的材料制成的小型旋转体模。在10°至80°的角度范围内比较了移动目标的真实速度和多普勒测量的最大速度。结果表明,频谱多普勒将最高速度高估了158%。对于50°-80°的光束目标角,理论速度误差与测量误差之间存在良好的一致性(<10%)。但是,对于10°-40°的角度,一致性不太好(> 50%)。该体模能够验证临床前超声中的血流速度测量性能。

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