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首页> 外文期刊>Ultrasound in Medicine and Biology >The Intravascular ultrasound elasticity-palpography technique revisited: A reliable tool for the invivo detection of vulnerable coronary atherosclerotic plaques
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The Intravascular ultrasound elasticity-palpography technique revisited: A reliable tool for the invivo detection of vulnerable coronary atherosclerotic plaques

机译：血管内超声弹力回波技术的再探：一种可靠的工具，用于体内检测脆弱的冠状动脉粥样硬化斑块

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摘要

Critical to the detection of vulnerable plaques (VPs) is quantification of their mechanical properties. On the basis of intravascular ultrasound (IVUS) echograms and strain images, E. I. Céspedes, C. L. de Korte CL and A. F. van der Steen (Ultrasound Med Biol 2000;26:385-396) proposed an elasticity-palpography technique (E-PT) to estimate the apparent stress-strain modulus palpogram of the thick endoluminal layer of the arterial wall. However, this approach suffers from major limitations because it was developed for homogeneous, circular and concentric VPs. The present study was therefore designed to improve the E-PT by considering the anatomic shape of the VP. This improved E-PT was successfully applied to six coronary lesions of patients imaged invivo with IVUS. Our results indicate that the mean relative error of the stress-strain modulus decreased from 61.02 ± 9.01% to 15.12 ± 12.57% when the IE-PT was used instead of the E-PT. The accuracy of the stress-strain modulus palpograms computed using the improved theoretical framework was also investigated with respect to noise, which may affect prediction of plaque vulnerability.
机译：对易损斑块（VP）的检测至关重要的是量化其力学性能。 EICéspedes，CL de Korte CL和AF van der Steen（Ultrasound Med Biol 2000; 26：385-396）基于血管内超声（IVUS）回波图和应变图像，提出了一种弹性手法（E-PT）估计动脉壁厚腔内层的表观应力-应变模量制图。但是，由于该方法是为均质，圆形和同心VP开发的，因此存在很大的局限性。因此，本研究旨在通过考虑VP的解剖形状来改善E-PT。这种改进的E-PT已成功应用于IVUS体内成像患者的六个冠状动脉病变。我们的结果表明，当使用IE-PT代替E-PT时，应力-应变模量的平均相对误差从61.02±9.01％降低到15.12±12.57％。还针对噪声研究了使用改进的理论框架计算的应力-应变模量制图的准确性，这可能会影响斑块易损性的预测。

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