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Buddleja davidii stem cells limit photodamage

机译:Buddleja davidii干细胞限制光损伤

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摘要

Constant exposure of the skin to various types of mechanical and environmental stresses such as reactive oxidative species, air pollutants and, particularly, ultraviolet radiations, namely UVA, UVB and UVC, can cause damage by activating a complex cascade of biochemical mechanisms, especially via the generation of free radicals. Indeed, once endogenous antioxidative defences have been exhausted, these free radicals are free to damage the molecular structures of the cell (proteins, lipids and DNA). Moreover, as a consequence of UV exposure, inflammatory phenomena not only lead to the generation of further free radicals, but also trigger the release of chemical mediators.
机译:皮肤不断暴露于各种类型的机械和环境压力下,例如反应性氧化物质,空气污染物,尤其是紫外线辐射(即UVA,UVB和UVC),可能会通过激活复杂的生物化学机制(尤其是通过化学反应)而造成损害。自由基的产生。的确,一旦内源性抗氧化防御作用被耗尽,这些自由基就会自由地破坏细胞的分子结构(蛋白质,脂质和DNA)。此外,由于暴露于紫外线,炎症现象不仅导致产生更多的自由基,而且还触发了化学介质的释放。

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