...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pathology case reviews. >Meconium-Associated Vascular Necrosis
【24h】

Meconium-Associated Vascular Necrosis

机译：胎粪相关性血管坏死

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

An infant with all of the cardinal features of birth asphyxia as specified by the American College of Obstetrics and Gynecology went on to develop severe spastic quadriplegic cerebral palsy. However, placental pathology revealed 2 significant lesions indicating a period of subacute vascular injury and severe hypoxia extending 6 to 12 hours or more prior to the delivery. The first, meconium-associated vascular necrosis, is a fetal large vessel vasculopathy related to apoptosis of vascular smooth muscle cells secondary to the toxic effects of prolonged exposure to high concentrations of meconium. The second, markedly increased circulating fetal nucleated red blood cells, is an adaptive response by fetal hematopoietic tissues to reduced circulating fetal oxygen tension.
机译：按照美国妇产科学院的规定，具有出生窒息的所有基本特征的婴儿继续发展为严重的痉挛性四肢瘫痪性脑瘫。然而，胎盘病理学显示有2个明显的病变，表明亚急性血管损伤和严重的缺氧持续了6到12个小时或更长时间。首先是与胎粪有关的血管坏死，是一种胎儿大血管病变，与长期暴露于高浓度胎粪的毒性作用有关，与血管平滑肌细胞凋亡有关。第二种是胎儿循环的有核红细胞明显增加，是胎儿造血组织对降低胎儿的循环血氧张力的适应性反应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号