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Melanotic schwannoma mimicking metastatic pigmented melanoma: a pitfall in cytological diagnosis

机译:模仿转移性黑色素瘤的黑色素神经鞘瘤:细胞学诊断的陷阱

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摘要

Melanotic schwannomas are rare tumours and less than 100 cases have been reported in the literature. In 40-50% of cases psammoma bodies are identified and these tumours have been termed 'psammomatous melanotic schwannomas'. Melanotic schwannomas are a component of Carney's complex, a syndrome in which patients manifest myxomas, spotty pigmentation (lentigenes and epithelioid blue naevi/pigmented epithelioid melanocytomas) and endocrine hyperactivity, along with a variety of other tumours including large cell calcifying Sertoli cell tumours, thyroid tumours and ductal adenomas of the breast.2 Melanotic schwannomas occur most commonly in a paraspinal location, but may also arise in the oral cavity, skin, soft tissue, bone and the gastrointestinal tract.1 The fine needle biopsy (FNB) features of melanotic schwannomas have been rarely reported. We describe the cytological features of a case of melanotic schwannoma which resembled metastatic melanoma.
机译:黑色素神经鞘瘤是罕见的肿瘤,文献报道少于100例。在40%至50%的病例中,发现了肺腺瘤体,这些肿瘤被称为“肺部黑色素化神经鞘瘤”。黑色素神经鞘瘤是卡尼氏综合症的一个组成部分,该综合症是一种患者表现为粘液瘤,斑点状色素沉着(色素生成素和上皮样蓝色痣/色素上皮样黑素细胞瘤)和内分泌机能亢进,以及多种其他肿瘤,包括大细胞钙化支持性细胞瘤,甲状腺黑色素瘤神经鞘瘤最常发生在椎旁位置,但也可能出现在口腔,皮肤,软组织,骨骼和胃肠道中。1黑色素瘤的细针穿刺活检(FNB)特征schwannomas鲜有报道。我们描述了与转移性黑色素瘤类似的黑色素性神经鞘瘤病例的细胞学特征。

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