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首页> 外文期刊>Technology in cancer research & treatment. >Management of Liver Cancer Argon-helium Knife Therapy with Functional Computer Tomography Perfusion Imaging
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Management of Liver Cancer Argon-helium Knife Therapy with Functional Computer Tomography Perfusion Imaging

机译：功能性计算机断层扫描灌注成像技术对肝癌氩氦刀治疗的管理

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The objective of this study was to observe the change in blood perfusion of liver cancer following argon-helium knife treatment with functional computer tomography perfusion imaging. Twenty-seven patients with primary liver cancer treated with argon-helium knife and were included in this study. Plain computer tomography (CT) and computer tomography perfusion (CTP) imaging were conducted in all patients before and after treatment. Perfusion parameters including blood flows, blood volume, hepatic artery perfusion fraction, hepatic artery perfusion, and hepatic portal venous perfusion were used for evaluating therapeutic effect. All parameters in liver cancer were significantly decreased after argon-helium knife treatment (p < 0.05 to all). Significant decrease in hepatic artery perfusion was also observed in pericancerous liver tissue, but other parameters kept constant. CT perfusion imaging is able to detect decrease in blood perfusion of liver cancer post-argon-helium knife therapy. Therefore, CTP imaging would play an important role for liver cancer management followed argon-helium knife therapy.
机译：这项研究的目的是观察功能性计算机断层扫描灌注成像在氩氦刀治疗后肝癌血液灌注的变化。本研究纳入了27例用氩氦刀治疗的原发性肝癌患者。在治疗前后对所有患者进行了普通计算机断层扫描（CT）和计算机断层扫描灌注（CTP）成像。使用包括血流量，血容量，肝动脉灌注分数，肝动脉灌注和肝门静脉灌注的灌注参数来评估治疗效果。氩氦刀治疗后，肝癌中的所有参数均显着降低（全部p <0.05）。在癌变的肝组织中也观察到肝动脉灌注的显着减少，但其他参数保持不变。 CT灌注成像能够检测出氩氦刀治疗后肝癌血液灌注的减少。因此，CTP成像将在氩氦刀治疗后对肝癌的治疗中发挥重要作用。

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