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首页> 外文期刊>The American Journal of Surgery >Recurrent skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus requiring operative debridement.
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Recurrent skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus requiring operative debridement.

机译：耐甲氧西林金黄色葡萄球菌引起的皮肤和软组织反复感染需要手术清创。

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摘要

BACKGROUND: The aim of this study was to examine clinical factors associated with the recurrence of community-onset skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus. METHODS: An observational case-comparison study based on a retrospective review of medical records was conducted in a public health system. All patients with community-onset skin and soft tissue infections caused by methicillin-resistant S aureus who underwent operative debridement from January 1999 to December 2003 were included. The outcome of interest was recurrence within 1 year. RESULTS: Two hundred fifty-three patients met the criteria for inclusion. Fifty-three (21%) patients returned with recurrent episodes. These patients were compared with 200 patients (79%) who did not develop recurrence. On multivariate analysis, factors independently predictive of recurrence were medical history of abscess requiring surgical debridement within the previous year (adjusted odds ratio, 2.6; 95% confidence interval, 1.4-5.0; P = .002) and obesity (adjusted odds ratio, 3.4; 95% confidence interval, 1.4-8.8; P = .008). CONCLUSIONS: Patients with obesity or histories of methicillin-resistant S aureus infection are at significantly increased risk for recurrent soft tissue infection.
机译：背景：这项研究的目的是检查与耐甲氧西林金黄色葡萄球菌引起的社区发作的皮肤和软组织感染复发相关的临床因素。方法：在公共卫生系统中基于回顾性病历回顾性病例比较研究。纳入了所有由耐甲氧西林金黄色葡萄球菌引起的社区发作的皮肤和软组织感染的患者，这些患者在1999年1月至2003年12月接受手术清创术。感兴趣的结果是1年内复发。结果：253例患者符合纳入标准。 53例（21％）患者复发发作。将这些患者与未复发的200例患者（79％）进行了比较。在多变量分析中，独立预测复发的因素是上一年内需要手术清创的脓肿病史（调整后的优势比，2.6; 95％置信区间，1.4-5.0; P = .002）和肥胖症（调整后的优势比，3.4） ; 95％置信区间1.4-8.8; P = 0.008）。结论：肥胖或耐甲氧西林金黄色葡萄球菌病史的患者复发软组织感染的风险显着增加。

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