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首页> 外文期刊>The American journal of otology >Experimental investigations of the use of cartilage in tympanic membrane reconstruction.
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Experimental investigations of the use of cartilage in tympanic membrane reconstruction.

机译：在鼓膜重建中使用软骨的实验研究。

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BACKGROUND: Temporalis fascia, perichondrium, and cartilage are commonly used for reconstruction of the tympanic membrane in middle ear surgery. Cartilage grafts offer the advantage of higher mechanical stability, particularly in cases of chronic tubal dysfunction, adhesive processes, or total defects of the tympanic membrane, in contrast to fascia and perichondrium, which presumably offer better acoustic quality. HYPOTHESIS: The purpose of this study was to determine the acoustic transfer characteristics of cartilage of varying thickness and its mechanical deformation when exposed to fluctuations in atmospheric pressure. METHOD: Ten pairs of cartilage specimens from the cavum conchae and the tragus were obtained from fresh human cadavers. Young's modulus was determined by mechanical tension tests and statistically evaluated using the t test. The acoustic transfer characteristics of an additional 10 specimens were measured by a laser Doppler Interferometer after stimulation with white noise in an external auditory canal--tympanic membrane model. Mechanical stability was determined by measuring displacement of the cartilage using static pressure loads of < or = 4 kPa. RESULTS: Young's modulus determinations for conchal and tragal cartilage were 3.4 N/mm2 and 2.8 N/mm2, respectively, but the difference was not significant. Acoustic testing showed a 5-dB higher vibration amplitude in the midfrequency range for conchal compared with tragal cartilage, but the difference was not significant. Reducing cartilage thickness led to an improvement of its acoustic transfer qualities, with a thickness < or = 500 microm resulting in an acceptable acoustic transfer loss compared with the tympanic membrane. CONCLUSION: Both conchal and tragal cartilage are useful for reconstruction of the tympanic membrane from the perspective of their acoustic properties. The acoustic transfer loss of cartilage can be reduced by decreasing its thickness. A thickness of 500 microm is regarded as a good compromise between sufficient mechanical stability and low acoustic transfer loss.
机译：背景：颞中筋膜，软骨膜和软骨通常用于中耳手术中的鼓膜重建。软骨移植物具有更高的机械稳定性，特别是在慢性输卵管功能不全，粘连过程或鼓膜完全缺损的情况下，与筋膜和软骨膜相反，后者可以提供更好的声音质量。假设：这项研究的目的是确定厚度变化的软骨的声传递特性及其在大气压力波动下的机械变形。方法：从新鲜的人类尸体中获得十对从鼻甲和耳屏的软骨标本。杨氏模量通过机械张力测试确定，并使用t检验进行统计学评估。在外耳道-鼓膜模型中用白噪声刺激后，再用激光多普勒干涉仪测量另外10个样本的声传递特性。通过使用≤4 kPa的静压力载荷测量软骨的位移来确定机械稳定性。结果：确定的共生和骨软骨的杨氏模量分别为3.4 N / mm2和2.8 N / mm2，但差异不显着。声学测试显示，与hal骨软骨相比，中音在中音范围内的振动幅度高了5 dB，但差异不显着。降低软骨厚度导致其声音传递质量得到改善，厚度小于或等于500微米时，与鼓膜相比，可接受的声音传递损失。结论：从声学特性来看，共生软骨和小脑软骨均可用于重建鼓膜。软骨的声传递损失可以通过减小其厚度来减小。 500微米的厚度被认为是足够的机械稳定性和低的声传递损耗之间的良好折衷。

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